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Can Pirfenidone and Nintedanib Be Alternative Treatment Options for Radiation Pneumonitis?

作者信息

Coban Hikmet, Colak Mustafa, Yumrukuz Şenel Merve, Gunes Muzaffer, Sarioglu Nurhan, Erel Fuat

机构信息

Balikesir University Faculty of Medicine, Department of Pulmonology, Balikesir, Türkiye.

出版信息

Medeni Med J. 2025 Jun 26;40(2):114-115. doi: 10.4274/MMJ.galenos.2025.87393.

DOI:10.4274/MMJ.galenos.2025.87393

PMID:40569827

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12203438/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6558/12203438/6fc37aebfbd0/MedeniMedJ-40-2-114-figure-1.jpg

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Can Pirfenidone and Nintedanib Be Alternative Treatment Options for Radiation Pneumonitis?

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本文引用的文献

Nintedanib reduces radiation-induced microscopic lung fibrosis but this cannot be monitored by CT imaging: A preclinical study with a high precision image-guided irradiator.

Radiother Oncol. 2017 Sep;124(3):482-487. doi: 10.1016/j.radonc.2017.07.014. Epub 2017 Jul 31.

Radiation Pneumonitis.

Clin Chest Med. 2017 Jun;38(2):201-208. doi: 10.1016/j.ccm.2016.12.004. Epub 2017 Mar 1.

Oral pirfenidone in patients with chronic fibrosis resulting from radiotherapy: a pilot study.

Radiat Oncol. 2007 May 31;2:19. doi: 10.1186/1748-717X-2-19.

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Can Pirfenidone and Nintedanib Be Alternative Treatment Options for Radiation Pneumonitis?

作者信息

Coban Hikmet, Colak Mustafa, Yumrukuz Şenel Merve, Gunes Muzaffer, Sarioglu Nurhan, Erel Fuat

机构信息

Balikesir University Faculty of Medicine, Department of Pulmonology, Balikesir, Türkiye.

出版信息

Medeni Med J. 2025 Jun 26;40(2):114-115. doi: 10.4274/MMJ.galenos.2025.87393.

DOI:10.4274/MMJ.galenos.2025.87393

PMID:40569827

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12203438/

Abstract

摘要

相似文献

Can Pirfenidone and Nintedanib Be Alternative Treatment Options for Radiation Pneumonitis?

Medeni Med J. 2025 Jun 26;40(2):114-115. doi: 10.4274/MMJ.galenos.2025.87393.

Glasgow prognostic score and body mass index predict short-term discontinuation of the antifibrotic agents pirfenidone and nintedanib.

Respir Investig. 2024 May;62(3):388-394. doi: 10.1016/j.resinv.2024.02.012. Epub 2024 Mar 8.

Efficacy and safety of pharmacological treatments for autoimmune disease-associated interstitial lung disease: A systematic review and network meta-analysis.

Semin Arthritis Rheum. 2024 Oct;68:152500. doi: 10.1016/j.semarthrit.2024.152500. Epub 2024 Jun 27.

Efficacy of Pirfenidone and Nintedanib in Interstitial Lung Diseases Other than Idiopathic Pulmonary Fibrosis: A Systematic Review.

Int J Mol Sci. 2023 Apr 25;24(9):7849. doi: 10.3390/ijms24097849.

The tolerability and efficacy of antifibrotic therapy in patients with idiopathic pulmonary fibrosis: Results from a real-world study.

Pulm Pharmacol Ther. 2024 Mar;84:102287. doi: 10.1016/j.pupt.2024.102287. Epub 2024 Jan 17.

Differential Discontinuation Profiles between Pirfenidone and Nintedanib in Patients with Idiopathic Pulmonary Fibrosis.

Cells. 2022 Jan 2;11(1):143. doi: 10.3390/cells11010143.

Impact of reduction in antifibrotic treatment on mortality in idiopathic pulmonary fibrosis.

Respir Med. 2022 Nov-Dec;204:107015. doi: 10.1016/j.rmed.2022.107015. Epub 2022 Oct 25.

BMC Pulm Med. 2020 Jul 11;20(1):188. doi: 10.1186/s12890-020-01224-5.

Real-World Study Analysing Progression and Survival of Patients with Idiopathic Pulmonary Fibrosis with Preserved Lung Function on Antifibrotic Treatment.

Adv Ther. 2021 Jan;38(1):268-277. doi: 10.1007/s12325-020-01523-7. Epub 2020 Oct 24.

Effectiveness and Safety of Pirfenidone and Nintedanib for Pulmonary Fibrosis in COVID-19-Induced Severe Pneumonia: An Interventional Study.

Cureus. 2022 Sep 21;14(9):e29435. doi: 10.7759/cureus.29435. eCollection 2022 Sep.

本文引用的文献

Nintedanib reduces radiation-induced microscopic lung fibrosis but this cannot be monitored by CT imaging: A preclinical study with a high precision image-guided irradiator.

Radiother Oncol. 2017 Sep;124(3):482-487. doi: 10.1016/j.radonc.2017.07.014. Epub 2017 Jul 31.

Radiation Pneumonitis.

Clin Chest Med. 2017 Jun;38(2):201-208. doi: 10.1016/j.ccm.2016.12.004. Epub 2017 Mar 1.

Oral pirfenidone in patients with chronic fibrosis resulting from radiotherapy: a pilot study.

Radiat Oncol. 2007 May 31;2:19. doi: 10.1186/1748-717X-2-19.