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Can Pirfenidone and Nintedanib Be Alternative Treatment Options for Radiation Pneumonitis?

作者信息

Coban Hikmet, Colak Mustafa, Yumrukuz Şenel Merve, Gunes Muzaffer, Sarioglu Nurhan, Erel Fuat

机构信息

Balikesir University Faculty of Medicine, Department of Pulmonology, Balikesir, Türkiye.

出版信息

Medeni Med J. 2025 Jun 26;40(2):114-115. doi: 10.4274/MMJ.galenos.2025.87393.

DOI:10.4274/MMJ.galenos.2025.87393
PMID:40569827
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12203438/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6558/12203438/f48206aaa52b/MedeniMedJ-40-2-114-figure-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6558/12203438/6fc37aebfbd0/MedeniMedJ-40-2-114-figure-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6558/12203438/f48206aaa52b/MedeniMedJ-40-2-114-figure-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6558/12203438/6fc37aebfbd0/MedeniMedJ-40-2-114-figure-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6558/12203438/f48206aaa52b/MedeniMedJ-40-2-114-figure-2.jpg

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本文引用的文献

1
Nintedanib reduces radiation-induced microscopic lung fibrosis but this cannot be monitored by CT imaging: A preclinical study with a high precision image-guided irradiator.尼达尼布可减轻辐射诱导的微观肺纤维化，但无法通过CT成像进行监测：一项使用高精度图像引导照射器的临床前研究。
Radiother Oncol. 2017 Sep;124(3):482-487. doi: 10.1016/j.radonc.2017.07.014. Epub 2017 Jul 31.
2
Radiation Pneumonitis.放射性肺炎
Clin Chest Med. 2017 Jun;38(2):201-208. doi: 10.1016/j.ccm.2016.12.004. Epub 2017 Mar 1.
3
Oral pirfenidone in patients with chronic fibrosis resulting from radiotherapy: a pilot study.
口服吡非尼酮治疗放射性纤维化：一项初步研究。
Radiat Oncol. 2007 May 31;2:19. doi: 10.1186/1748-717X-2-19.