Basavalingu Deepashri, Elojeimy Saeed, Mercer Megan K, Itani Malak, Revels Jonathan W, Blacklock Lisa C, Zuckier Lionel S, Wang Sherry S, Kolokythas Orpheus, Behnia Fatemeh
From the Department of Radiology, University of Washington, 1959 NE Pacific St, Seattle, WA 98195 (D.B., O.K., F.B.); Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC (S.E., M.K.M.); Department of Radiology, Washington University in St. Louis, St. Louis, Mo (M.I.); Department of Radiology, New York University Grossman School of Medicine, New York, NY (J.W.R.); Department of Radiology, University of New Mexico, Albuquerque, NM (L.C.B.); Department of Radiology, Division of Nuclear Medicine, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY (L.S.Z.); and Department of Radiology, Mayo Clinic, Rochester, Minn (S.S.W.).
Radiographics. 2025 Jul;45(7):e240207. doi: 10.1148/rg.240207.
Although lymphoscintigraphy is most commonly used for sentinel lymph node mapping, it can also be helpful for evaluating lymphedema, lymphatic malformations, lymphatic leaks, chylous ascites, and chylothorax. Assessment for lymphedema is important because this condition poses significant clinical challenges, and early diagnosis is essential for timely intervention and prevention of complications. Lymphoscintigraphy is a valuable radiologic tool for distinguishing lymphatic causes of edema from nonlymphatic ones, with findings of lymphedema including absent, asymmetric, or delayed drainage from the injection site; dermal backflow; and reduced activity in the inguinal or axillary lymph nodes at lower extremity and upper extremity lymphoscintigraphy. Other supporting evidence of lymphedema may include collateral lymphatic channels and visualization of the deep lymphatic nodes. Additional imaging modalities, such as fluorescence lymphangiography, US, and MR lymphangiography, can also aid in lymphedema assessment. The authors provide an overview of lymphatic physiology, image acquisition, and image interpretation. RSNA, 2025.
尽管淋巴闪烁显像最常用于前哨淋巴结定位，但它也有助于评估淋巴水肿、淋巴管畸形、淋巴漏、乳糜腹水和乳糜胸。对淋巴水肿进行评估很重要，因为这种情况带来了重大的临床挑战，早期诊断对于及时干预和预防并发症至关重要。淋巴闪烁显像是一种有价值的放射学工具，可用于区分水肿的淋巴性病因和非淋巴性病因，淋巴水肿的表现包括注射部位引流缺失、不对称或延迟；真皮反流；以及在下肢和上肢淋巴闪烁显像中腹股沟或腋窝淋巴结活性降低。淋巴水肿的其他支持性证据可能包括侧支淋巴管和深部淋巴结的显影。其他成像方式，如荧光淋巴管造影、超声和磁共振淋巴管造影，也有助于淋巴水肿评估。作者提供了淋巴生理学、图像采集和图像解读的概述。RSNA，2025年。
