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A trial of fetal cells for Parkinson's disease brings lessons for the field.

作者信息

Tabar Viviane

机构信息

Department of Neurosurgery, Cancer Biology and Genetics and Center for Stem Cell Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

出版信息

Nat Biotechnol. 2025 Jun 26. doi: 10.1038/s41587-025-02742-5.

DOI:10.1038/s41587-025-02742-5
PMID:40571691
Abstract
摘要

相似文献

1
A trial of fetal cells for Parkinson's disease brings lessons for the field.一项针对帕金森病的胎儿细胞试验为该领域带来了经验教训。
Nat Biotechnol. 2025 Jun 26. doi: 10.1038/s41587-025-02742-5.
2
Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease.用于路易体痴呆、帕金森病痴呆及帕金森病认知障碍的胆碱酯酶抑制剂
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J Parkinsons Dis. 2024 Nov;14(8):1659-1676. doi: 10.1177/1877718X241301041. Epub 2024 Dec 27.
4
Helicobacter pylori eradication for Parkinson's disease.根除幽门螺杆菌治疗帕金森病。
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Self-Management Systems for Patients and Clinicians in Parkinson's Disease Care: A Scoping Review.帕金森病护理中患者和临床医生的自我管理系统:范围综述。
J Parkinsons Dis. 2024;14(7):1387-1404. doi: 10.3233/JPD-240137.
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The Long-Term Impact of Levodopa/Carbidopa Intestinal Gel on 'Off'-time in Patients with Advanced Parkinson's Disease: A Systematic Review.左旋多巴/卡比多巴肠凝胶对晚期帕金森病患者“关”期的长期影响:一项系统评价
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本文引用的文献

1
The TransEuro open-label trial of human fetal ventral mesencephalic transplantation in patients with moderate Parkinson's disease.人类胎儿腹侧中脑移植治疗中度帕金森病的泛欧开放标签试验。
Nat Biotechnol. 2025 May 2. doi: 10.1038/s41587-025-02567-2.
2
Phase I trial of hES cell-derived dopaminergic neurons for Parkinson's disease.用于帕金森病的人胚胎干细胞源性多巴胺能神经元的I期试验。
Nature. 2025 May;641(8064):978-983. doi: 10.1038/s41586-025-08845-y. Epub 2025 Apr 16.
3
Phase I/II trial of iPS-cell-derived dopaminergic cells for Parkinson's disease.
用于帕金森病的诱导多能干细胞衍生多巴胺能细胞的I/II期试验。
Nature. 2025 May;641(8064):971-977. doi: 10.1038/s41586-025-08700-0. Epub 2025 Apr 16.
4
Diagnosis and Treatment of Parkinson Disease: A Review.帕金森病的诊断与治疗:综述。
JAMA. 2020 Feb 11;323(6):548-560. doi: 10.1001/jama.2019.22360.
5
The Parkinson Pandemic-A Call to Action.帕金森病大流行——行动呼吁
JAMA Neurol. 2018 Jan 1;75(1):9-10. doi: 10.1001/jamaneurol.2017.3299.
6
Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain.在退化的帕金森病大脑中,移植后24年仍维持着广泛的移植源性多巴胺能神经支配。
Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):6544-9. doi: 10.1073/pnas.1605245113. Epub 2016 May 2.
7
Serotonergic neurons mediate dyskinesia side effects in Parkinson's patients with neural transplants.血清素能神经元介导帕金森病患者神经移植后的运动障碍副作用。
Sci Transl Med. 2010 Jun 30;2(38):38ra46. doi: 10.1126/scitranslmed.3000976.
8
A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease.帕金森病双侧胎儿黑质移植的双盲对照试验。
Ann Neurol. 2003 Sep;54(3):403-14. doi: 10.1002/ana.10720.
9
Blinded positron emission tomography study of dopamine cell implantation for Parkinson's disease.帕金森病多巴胺细胞植入的盲法正电子发射断层扫描研究。
Ann Neurol. 2001 Aug;50(2):181-7. doi: 10.1002/ana.1075.
10
Transplantation of embryonic dopamine neurons for severe Parkinson's disease.胚胎多巴胺神经元移植治疗重度帕金森病
N Engl J Med. 2001 Mar 8;344(10):710-9. doi: 10.1056/NEJM200103083441002.