Misirovs Rasads, Kamusella Anna, Miller Michael, Majumdar Samit
Department of Otorhinolaryngology, NHS Lothian, Edinburgh EH16 4SA, UK.
Department of Doctoral Studies, Riga Stradins University, LV-1007 Riga, Latvia.
Medicina (Kaunas). 2025 Jun 6;61(6):1047. doi: 10.3390/medicina61061047.
In the United Kingdom, some patients with food bolus obstruction (FBO) are admitted under the care of ear, nose, and throat (ENT) doctors. In the literature, eosinophilic oesophagitis (EoE) is the most common cause of FBO. We analysed ENT FBO admissions and interventions used in our hospital to investigate for EoE. This paper details a retrospective study of adult FBO admissions to an ENT ward from January 2016 to December 2019 at a single centre. In total, 120 patients were admitted. Half of the patients required instrumentation to resolve the obstruction-31% underwent rigid oesophagoscopy (RO) and 69% oesophagogastroduodenoscopy (OGD). Biopsies were taken during 48% of inpatient OGDs and 5% of ROs. 48% had a histopathological diagnosis of EoE. There was no mention of a specific number of eosinophils per high-power field in 53% of EoE pathology reports. Potentially, some patients were EoE-negative due to an inadequate number of biopsies taken-71% of patients had an insufficient number of biopsies to exclude EoE. A total of 56% of all patients with FBO did not undergo inpatient or outpatient OGDs with biopsies. Biopsies were not taken in all FBO patients undergoing oesophagoscopy, leaving EoE underdiagnosed. Follow-up arrangements were often suboptimal to exclude EoE.
在英国,一些患有食团梗阻(FBO)的患者由耳鼻喉科(ENT)医生负责收治。在文献中,嗜酸性粒细胞性食管炎(EoE)是FBO最常见的病因。我们分析了我院用于调查EoE的耳鼻喉科FBO收治情况及干预措施。本文详细介绍了一项对2016年1月至2019年12月期间在单一中心的耳鼻喉科病房收治的成年FBO患者的回顾性研究。总共收治了120例患者。一半的患者需要借助器械来解除梗阻,其中31%接受了硬式食管镜检查(RO),69%接受了食管胃十二指肠镜检查(OGD)。在48%的住院OGD检查和5%的RO检查过程中进行了活检。48%的患者有EoE的组织病理学诊断。在53%的EoE病理报告中未提及每高倍视野下嗜酸性粒细胞的具体数量。可能有些患者因活检数量不足而EoE诊断为阴性,71%的患者活检数量不足以排除EoE。所有FBO患者中共有56%未接受住院或门诊的OGD检查及活检。并非所有接受食管镜检查的FBO患者都进行了活检,导致EoE诊断不足。随访安排往往也欠佳,无法排除EoE。