饮食干预对认知结果的影响。

Effects of Dietary Interventions on Cognitive Outcomes.

作者信息

Charbit Judith, Vidal Jean-Sébastien, Hanon Olivier

机构信息

Service Gérontologie Hôpital Broca, Université Paris Cité, AP-HP, F-75013 Paris, France.

出版信息

Nutrients. 2025 Jun 9;17(12):1964. doi: 10.3390/nu17121964.

Abstract

Cognitive aging is a complex, multifactorial process influenced by genetic, metabolic, and environmental factors. Among modifiable risk factors, nutrition has emerged as a promising target to preserve cognitive function. This review provides a comprehensive overview of the impact of dietary interventions-including specific nutrients and dietary patterns-on cognitive domains (memory, executive function, global cognition) and mental health. Recent findings: multinutrient supplementation, particularly combinations of B vitamins and omega-3 fatty acids, appears beneficial for episodic memory, especially in individuals with metabolic risk or early cognitive impairment. Antioxidant-rich diets and the MIND diet are consistently associated with better memory and global cognitive outcomes in observational studies. Effects on executive function and mental health remain heterogeneous, although subgroups such as those with mild cognitive impairment or depression may derive benefit. Evidence from interventional studies remains limited by methodological variability. In conclusion, dietary interventions offer a safe and promising approach to support cognitive health in aging. Future research should focus on developing personalized, multidomain prevention models tailored to individual risk profiles.

摘要

认知衰老 是一个复杂的、多因素的过程,受遗传、代谢和环境因素影响。在可改变的风险因素中,营养已成为维持认知功能的一个有前景的目标。本综述全面概述了饮食干预(包括特定营养素和饮食模式)对认知领域(记忆、执行功能、整体认知)和心理健康的影响。最新研究结果:多种营养素补充剂,特别是B族维生素和ω-3脂肪酸的组合,似乎对情景记忆有益,尤其是在有代谢风险或早期认知障碍的个体中。在观察性研究中,富含抗氧化剂的饮食和MIND饮食始终与更好的记忆力和整体认知结果相关。对执行功能和心理健康的影响仍然存在异质性,尽管轻度认知障碍或抑郁症等亚组可能会从中受益。干预性研究的证据仍然受到方法学变异性的限制。总之,饮食干预为支持老年人的认知健康提供了一种安全且有前景的方法。未来的研究应专注于开发针对个体风险特征的个性化、多领域预防模型。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索