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Nirsevimab Immunisation Significantly Reduces Respiratory Syncytial Virus-Associated Bronchiolitis Hospitalisations and Alters Seasonal Patterns.尼塞韦单抗免疫接种显著降低呼吸道合胞病毒相关细支气管炎的住院率并改变季节性模式。
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本文引用的文献

1
Real-world effectiveness of RSVpreF vaccination during pregnancy against RSV-associated lower respiratory tract disease leading to hospitalisation in infants during the 2024 RSV season in Argentina (BERNI study): a multicentre, retrospective, test-negative, case-control study.在阿根廷2024年呼吸道合胞病毒(RSV)流行季,孕期接种RSVpreF疫苗预防婴儿因RSV相关下呼吸道疾病住院的真实世界有效性(BERNI研究):一项多中心、回顾性、检测阴性的病例对照研究
Lancet Infect Dis. 2025 May 5. doi: 10.1016/S1473-3099(25)00156-2.
2
Real-world effectiveness of nirsevimab against respiratory syncytial virus disease in infants: a systematic review and meta-analysis.尼塞韦单抗对婴儿呼吸道合胞病毒疾病的真实世界有效性:一项系统评价和荟萃分析。
Lancet Child Adolesc Health. 2025 Jun;9(6):393-403. doi: 10.1016/S2352-4642(25)00093-8. Epub 2025 May 1.
3
Impact of Nirsevimab on RSV and Non-RSV Severe Respiratory Infections in Hospitalized Infants.尼塞韦单抗对住院婴儿呼吸道合胞病毒及非呼吸道合胞病毒所致严重呼吸道感染的影响
Influenza Other Respir Viruses. 2025 May;19(5):e70105. doi: 10.1111/irv.70105.
4
Genotypic and phenotypic characterisation of respiratory syncytial virus after nirsevimab breakthrough infections: a large, multicentre, observational, real-world study.在接受尼塞韦单抗突破性感染后呼吸道合胞病毒的基因和表型特征:一项大型、多中心、观察性、真实世界研究。
Lancet Infect Dis. 2025 Mar;25(3):301-311. doi: 10.1016/S1473-3099(24)00570-X. Epub 2024 Oct 14.
5
Nirsevimab and Acute Bronchiolitis Episodes in Pediatric Emergency Departments.尼赛珠单抗与儿科急诊急性细支气管炎发作
Pediatrics. 2024 Oct 1;154(4). doi: 10.1542/peds.2024-066584.
6
Single-Dose Nirsevimab for Prevention of RSV in Preterm Infants.尼氏司他单抗单剂预防早产儿 RSV 感染。
N Engl J Med. 2020 Jul 30;383(5):415-425. doi: 10.1056/NEJMoa1913556.

Respiratory syncytial virus prophylaxis with nirsevimab: impact beyond hospitalisations.

作者信息

Calvo Cristina, García-García María Luz

机构信息

Paediatric Infectious and Tropical Diseases Department, La Paz University Hospital, Institute for Health Research IdiPAZ, Madrid, Spain.

CIBERINFEC, Carlos III Health Institute, Madrid, Spain.

出版信息

Lancet Reg Health Eur. 2025 Jun 11;55:101349. doi: 10.1016/j.lanepe.2025.101349. eCollection 2025 Aug.

DOI:10.1016/j.lanepe.2025.101349
PMID:40575468
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12197877/
Abstract
摘要