Mizuno S, Funahashi H, Fujimoto M, Sugiura H, Takeuchi M, Satoh Y, Nakanishi N, Fukatsu T, Nakashima N
Gan No Rinsho. 1985 Aug;31(10):1253-6.
Sinus histiocytosis in the regional lymph nodes of 45 patients with breast cancer who had undergone extended radical mastectomy was studied by histological examination of 2,294 resected lymph nodes. Sinus histiocytosis was divided into three grades, marked, moderate, and mild to negative, by Ohmori's classification. The results indicated that: 1) sinus histiocytosis correlates fairly well with clinical stage, especially with the n-factor, and 2) the degree of sinus histiocytosis shows little difference between three groups of regional lymph nodes. The authors concluded that sinus histiocytosis dominates the prognosis and represents some aspect of a reticuloendothelial response of the whole body to carcinoma.
对45例接受了扩大根治性乳房切除术的乳腺癌患者的区域淋巴结进行了窦组织细胞增多症研究，通过对2294个切除淋巴结进行组织学检查。根据大森分类法，将窦组织细胞增多症分为三个等级：显著、中度、轻度至阴性。结果表明：1）窦组织细胞增多症与临床分期密切相关，尤其是与n因子相关；2）三组区域淋巴结之间的窦组织细胞增多症程度差异不大。作者得出结论，窦组织细胞增多症主导预后，并代表了全身对癌的网状内皮反应的某些方面。
