Huerth Kimberly, Ohanenye Chiamaka, Quartey Andrea, Jackson Brooke, Callender Valerie
Dr. Huerth is with the Gateway Aesthetic Institute and Laser Center in Salt Lake City, Utah.
Mses. Ohanenye and Quartey are with the Lewis Katz School of Medicine at Temple University in Philadelphia, Pennsylvania.
J Clin Aesthet Dermatol. 2025 Jun;18(6):41-48.
This review examined studies published during the past two decades in which lasers were used to treat acne vulgaris. Its aim was to assess the mechanism, efficacy, and safety of lasers as a treatment modality for this vexingly common and potentially disfiguring condition.
PubMed searches were performed to identify articles published through December 2023 that discuss the use of lasers for the treatment of acne vulgaris.
Various lasers, including visible light, infrared, fractional ablative CO₂ lasers with isotretinoin, and two 1726-nm lasers approved by the United States Food and Drug Administration, show efficacy in treating acne vulgaris. Studies vary widely in their design, characteristics, and methodological rigor.
The available literature on using lasers to treat acne is limited by variability in study design, short-term follow up, and small sample sizes.
Lasers have demonstrated efficacy as primary or adjunctive treatment modalities for acne vulgaris in certain clinical scenarios. Larger randomized, controlled, double-blinded studies with sufficiently long follow-up periods and standardized objective measurements are needed to substantiate the efficacy of lasers in treating acne vulgaris.
本综述考察了过去二十年中发表的使用激光治疗寻常痤疮的研究。其目的是评估激光作为这种极为常见且可能毁容的疾病的一种治疗方式的作用机制、疗效和安全性。
进行PubMed检索，以识别截至2023年12月发表的讨论使用激光治疗寻常痤疮的文章。
各种激光，包括可见光、红外线、与异维A酸联用的剥脱性分数二氧化碳激光，以及两种美国食品药品监督管理局批准的1726纳米激光，在治疗寻常痤疮方面显示出疗效。研究在设计、特征和方法严谨性方面差异很大。
关于使用激光治疗痤疮的现有文献受到研究设计的变异性、短期随访和小样本量的限制。
在某些临床情况下，激光已证明作为寻常痤疮的主要或辅助治疗方式具有疗效。需要进行更大规模的随机、对照、双盲研究，并进行足够长时间的随访以及标准化的客观测量，以证实激光治疗寻常痤疮的疗效。
