Mohanty Monalisa, Jain Mantu, Tripathy Sujit Kumar, Tripathy Manisha, Kar Preetam Kumar, Mishra Baijayantimala, Mohapatra Prasanta Raghab
Department of Microbiology, Dr B C Roy Multispeciality Medical Research Centre, IIT, Kharagpur, Kharagpur 721302, West Bengal, India.
Department of Orthopaedics, All India Institute of Medical Sciences, Bhubaneswar 751019, Odisha, India.
World J Virol. 2025 Jun 25;14(2):102668. doi: 10.5501/wjv.v14.i2.102668.
BACKGROUND: Spinal tuberculosis (TB), also known as Pott's spine, remains a significant global health issue, particularly in regions with a high TB burden. The disease presents complex challenges in diagnosis, management, and treatment, prompting a growing interest in research over recent years. The advancements in imaging, diagnostics, and treatment strategies have driven an increased focus on publishing clinical outcomes, review articles, and case series related to spinal TB (STB). AIM: To perform a bibliometric analysis of STB research published over the last 5 years (2019-2023) to identify trends in publication volume, contributions by country, and the nature of the research being conducted. METHODS: A comprehensive bibliometric analysis was conducted using the PubMed database, focusing on research articles published between 2019 and 2023. Keywords such as "spine tuberculosis," "spinal TB," "TB spine," and "Pott's spine" were utilized to capture relevant publications. Articles were analyzed based on the type of research (, case reports, review articles, cohort studies, randomized controlled trials [RCTs]), number of citations, and country of origin based on the corresponding author's details. Further subgroup analysis was performed according to the TB burden in various countries to assess research trends in high-burden regions. RESULTS: A total of 528 articles met the inclusion criteria for this bibliometric analysis. The majority of articles were published between 2020 and 2023 (440/528; 83.3%), while the lowest number was published in 2019 (88/528; 16.7%). India led the global contributions with 25.8% of the total publications, followed by China (19.9%) and the United States (10.4%). Combined, African countries contributed 6.8% of the research on STB. Regarding the type of articles, case reports and case series dominated the literature (353/528; 66.9%), followed by review articles (120/528; 22.7%) and cohort studies (45/528; 8.5%). Only 1.9% (10/528) of the studies were RCTs. Countries such as the United States, Germany, the United Kingdom, and Japan have pioneered the use of artificial intelligence (AI) in the diagnostic processes for STB, while India, China, South Africa, and other countries have been pivotal in conducting clinical trials and improving clinical management strategies. CONCLUSION: This bibliometric analysis revealed a significant increase in STB research over the last 5 years, with India and China being the leading contributors. However, most publications are case reports or case series, with a limited number of RCTs. The results highlighted the need for more high-quality research, especially in terms of RCTs and innovations in diagnostic technologies. Additionally, the application of AI to STB diagnostics shows promise in developed countries, while high-burden countries are focusing on clinical trials and management strategies.
背景:脊柱结核,也称为波特氏病,仍然是一个重大的全球健康问题,尤其是在结核病负担较高的地区。该疾病在诊断、管理和治疗方面面临复杂挑战,近年来引发了越来越多的研究兴趣。影像学、诊断学和治疗策略的进步促使人们更加关注发表与脊柱结核(STB)相关的临床结果、综述文章和病例系列。 目的:对过去5年(2019 - 2023年)发表的STB研究进行文献计量分析,以确定发表数量趋势、各国的贡献以及所开展研究的性质。 方法:使用PubMed数据库进行全面的文献计量分析,重点关注2019年至2023年发表的研究文章。使用“脊柱结核”“脊髓结核”“结核性脊柱”和“波特氏脊柱”等关键词来获取相关出版物。根据研究类型(病例报告、综述文章、队列研究、随机对照试验[RCT])、引用次数以及根据通讯作者详细信息确定的原产国对文章进行分析。根据各国的结核病负担进行进一步的亚组分析,以评估高负担地区的研究趋势。 结果:共有528篇文章符合本次文献计量分析的纳入标准。大多数文章发表于2020年至2023年(440/528;83.3%),而发表数量最少的是2019年(88/528;16.7%)。印度以占总出版物的25.8%领先全球贡献,其次是中国(19.9%)和美国(10.4%)。非洲国家合计贡献了6.8%的STB研究。关于文章类型,病例报告和病例系列在文献中占主导地位(353/528;66.9%),其次是综述文章(120/528;22.7%)和队列研究(45/528;8.5%)。只有1.9%(10/528)的研究是RCT。美国、德国、英国和日本等国家率先在STB诊断过程中使用人工智能(AI),而印度、中国、南非和其他国家在开展临床试验和改进临床管理策略方面发挥了关键作用。 结论:本次文献计量分析显示,过去5年STB研究显著增加,印度和中国是主要贡献者。然而,大多数出版物是病例报告或病例系列,RCT数量有限。结果强调需要更多高质量研究,特别是在RCT和诊断技术创新方面。此外,AI在STB诊断中的应用在发达国家显示出前景,而高负担国家则专注于临床试验和管理策略。
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