Ishihara K, Hayasaka K, Ikegawa S, Kageshita T
Gan No Rinsho. 1985 Jul;31(9 Suppl):1073-8.
Malignant melanoma is one of the malignant tumors that prognosis is still gravest. Over the past years, a number of approaches have been used in treating this disease. And recently it has been said that multidisciplinary treatment should be needed for patients with stage 1 b and more advanced stage. At present, most frequently used combined chemotherapeutic regimens DAV (DTIC, ACNU and Vincristine) and PAV (Peplomycin, ACNU and Vincristine). With regard to radiotherapy, fast neutron and irradiation with hyperthermia has been recognized to be useful for malignant melanoma. Recently immunotherapy has been applied to the treatment of malignant melanoma. It is expected that multidisciplinary treatment will improve the prognosis of malignant melanoma.
恶性黑色素瘤是预后仍然最严重的恶性肿瘤之一。在过去几年中，已经采用了多种方法来治疗这种疾病。最近有人说，对于Ⅰb期及更晚期的患者需要进行多学科治疗。目前，最常用的联合化疗方案是DAV（达卡巴嗪、阿糖胞苷和长春新碱）和PAV（培洛霉素、阿糖胞苷和长春新碱）。关于放射治疗，快中子和热疗照射已被认为对恶性黑色素瘤有用。最近免疫疗法已被应用于恶性黑色素瘤的治疗。人们期望多学科治疗将改善恶性黑色素瘤的预后。
