T2细菌检测板在儿科造血细胞移植和细胞治疗患者中的应用：单中心经验
Use of T2Bacteria Panel in Pediatric Hematopoietic Cell Transplant and Cellular Therapy Patients: A Single-Center Experience.
作者信息
Hiskey Lisa, Glasgow Heather L, Hijano Diego, Ferrolino Jose, Dallas Ronald, Madden Renee M, Maron Gabriela, Hayden Randall T
机构信息
Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, United States.
Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, United States.
出版信息
J Pediatric Infect Dis Soc. 2025 Aug 7;14(7). doi: 10.1093/jpids/piaf059.
Abstract
We evaluated the use of the T2Bacteria panel for diagnosis of bloodstream infection in pediatric HCT/CT patients. Overall, the panel expedited recognition of bloodstream infections, providing results sooner than Gram stain and final blood culture identification. The T2Bacteria panel contributed to a change to appropriate therapy in 23% of patients with concordant positive results.
摘要
我们评估了T2Bacteria检测板在儿科造血干细胞移植/化疗患者血流感染诊断中的应用。总体而言，该检测板加快了血流感染的识别速度，比革兰氏染色和最终血培养鉴定更快地提供结果。在23%检测结果一致为阳性的患者中，T2Bacteria检测板促使治疗方案改为适当的治疗。
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本文引用的文献
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Incidence, Risk Factors and Outcome of Bloodstream Infections in Patients After Hematopoietic Stem-Cell Transplantation: A Single Center Study.造血干细胞移植患者血流感染的发病率、危险因素及结局：一项单中心研究
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Guideline for the Management of Fever and Neutropenia in Pediatric Patients With Cancer and Hematopoietic Cell Transplantation Recipients: 2023 Update.儿童癌症患者和造血细胞移植受者伴发热与中性粒细胞减少管理指南：2023 年更新版。
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Effective Rapid Diagnosis of Bacterial and Fungal Bloodstream Infections by T2 Magnetic Resonance Technology in the Pediatric Population.T2 磁共振技术在儿科人群中对细菌性和真菌性血流感染的快速有效诊断。
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