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本文引用的文献

1
Point-of-Care Method T2BacteriaPanel Enables a More Sensitive and Rapid Diagnosis of Bacterial Blood Stream Infections and a Shorter Time until Targeted Therapy than Blood Culture.即时检测方法T2细菌检测板能够比血培养更灵敏、快速地诊断细菌性血流感染,且能缩短开始靶向治疗的时间。
Microorganisms. 2024 May 11;12(5):967. doi: 10.3390/microorganisms12050967.
2
Incidence, Risk Factors and Outcome of Bloodstream Infections in Patients After Hematopoietic Stem-Cell Transplantation: A Single Center Study.造血干细胞移植患者血流感染的发病率、危险因素及结局:一项单中心研究
Indian J Hematol Blood Transfus. 2023 Apr 1;39(4):1-5. doi: 10.1007/s12288-023-01645-2.
3
Guideline for the Management of Fever and Neutropenia in Pediatric Patients With Cancer and Hematopoietic Cell Transplantation Recipients: 2023 Update.儿童癌症患者和造血细胞移植受者伴发热与中性粒细胞减少管理指南:2023 年更新版。
J Clin Oncol. 2023 Mar 20;41(9):1774-1785. doi: 10.1200/JCO.22.02224. Epub 2023 Jan 23.
4
Effective Rapid Diagnosis of Bacterial and Fungal Bloodstream Infections by T2 Magnetic Resonance Technology in the Pediatric Population.T2 磁共振技术在儿科人群中对细菌性和真菌性血流感染的快速有效诊断。
J Clin Microbiol. 2022 Oct 19;60(10):e0029222. doi: 10.1128/jcm.00292-22. Epub 2022 Sep 7.
5
Molecular diagnosis of bacteremia in a pediatric intensive care unit: a step forward.儿科重症监护病房菌血症的分子诊断:向前迈进了一步。
Future Microbiol. 2022 May;17:505-510. doi: 10.2217/fmb-2021-0154. Epub 2022 Mar 22.
6
Role of the T2Dx magnetic resonance assay in patients with suspected bloodstream infection: a single-centre real-world experience.T2Dx 磁共振检测法在疑似血流感染患者中的作用:单中心真实世界经验。
BMC Infect Dis. 2022 Feb 1;22(1):113. doi: 10.1186/s12879-022-07096-w.
7
In-depth analysis of T2Bacteria positive results in patients with concurrent negative blood culture: a case series.深入分析血培养阴性而 T2Bacteria 阳性患者的结果:病例系列。
BMC Infect Dis. 2020 May 7;20(1):326. doi: 10.1186/s12879-020-05049-9.
8
The T2Bacteria Assay Is a Sensitive and Rapid Detector of Bacteremia That Can Be Initiated in the Emergency Department and Has Potential to Favorably Influence Subsequent Therapy.T2Bacteria 检测法是一种灵敏、快速的菌血症检测方法,可在急诊科启动,有可能对后续治疗产生有利影响。
J Emerg Med. 2020 May;58(5):785-796. doi: 10.1016/j.jemermed.2019.11.028. Epub 2020 Jan 23.
9
Incidence, risk factors, and outcome of blood stream infections during the first 100 days post-pediatric allogeneic and autologous hematopoietic stem cell transplantations.儿童异基因和自体造血干细胞移植后 100 天内血流感染的发生率、危险因素和转归。
Pediatr Transplant. 2020 Feb;24(1):e13610. doi: 10.1111/petr.13610. Epub 2019 Nov 4.
10
Performance of the T2Bacteria Panel for Diagnosing Bloodstream Infections: A Diagnostic Accuracy Study.T2Bacteria Panel 用于诊断血流感染的性能:一项诊断准确性研究。
Ann Intern Med. 2019 Jun 18;170(12):845-852. doi: 10.7326/M18-2772. Epub 2019 May 14.

T2细菌检测板在儿科造血细胞移植和细胞治疗患者中的应用:单中心经验

Use of T2Bacteria Panel in Pediatric Hematopoietic Cell Transplant and Cellular Therapy Patients: A Single-Center Experience.

作者信息

Hiskey Lisa, Glasgow Heather L, Hijano Diego, Ferrolino Jose, Dallas Ronald, Madden Renee M, Maron Gabriela, Hayden Randall T

机构信息

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, United States.

Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, United States.

出版信息

J Pediatric Infect Dis Soc. 2025 Aug 7;14(7). doi: 10.1093/jpids/piaf059.

DOI:10.1093/jpids/piaf059
PMID:40576969
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12343080/
Abstract

We evaluated the use of the T2Bacteria panel for diagnosis of bloodstream infection in pediatric HCT/CT patients. Overall, the panel expedited recognition of bloodstream infections, providing results sooner than Gram stain and final blood culture identification. The T2Bacteria panel contributed to a change to appropriate therapy in 23% of patients with concordant positive results.

摘要

我们评估了T2Bacteria检测板在儿科造血干细胞移植/化疗患者血流感染诊断中的应用。总体而言,该检测板加快了血流感染的识别速度,比革兰氏染色和最终血培养鉴定更快地提供结果。在23%检测结果一致为阳性的患者中,T2Bacteria检测板促使治疗方案改为适当的治疗。