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骨-髌腱-骨同种异体移植对于前交叉韧带一期翻修术来说是安全有效的移植物:38例患者的连续系列研究,随访至少2年。

Bone-patellar tendon-bone allografts are safe and effective grafts for anterior cruciate ligament one-stage revision: A consecutive series of 38 patients with at least 2 years of follow up.

作者信息

Turati Marco, Anghilieri Filippo Maria, Crippa Marco, Piatti Massimiliano, Rigamonti Luca, Tassistro Elena, Trapletti Sabrina, Bigoni Marco

机构信息

Department of Orthopaedic and Trauma, Fondazione IRCCS San Gerardo dei Tintori, University of Milano-Bicocca, Monza, Italy; Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy; Transalpine Center of Paediatric Sports Medicine and Surgery, University of Milano-Bicocca, Monza, Italy; Department of Paediatric Orthopaedic Surgery, University Hospital Grenoble-Alpes, University Grenoble-Alpes, Grenoble, France.

Department of Orthopaedic and Trauma, San Leopoldo Mandic Hospital, Merate, Italy.

出版信息

Knee. 2025 Oct;56:354-365. doi: 10.1016/j.knee.2025.05.034. Epub 2025 Jun 26.

Abstract

BACKGROUND

Rupture of the anterior cruciate ligament is one of the most common injuries in sports. Although primary reconstruction is a successful procedure, failure is reported to occur in up to 13% of patients. In patients who complain of instability, revision surgery should be proposed and discussed with patients. The issue arising in this setting is the graft choice, being limited from the grafts used in primary surgery.

METHODS

We retrospectively enrolled 38 consecutive patients who had undergone ACL one-stage revision with bone-patellar tendon-bone (BPTB) allografts from a single center with at least 2 years of follow up. The clinical evaluation was based on PROMs In addition, we recorded the rate of allograft re-rupture and post-surgical complications.

RESULTS

Our series showed good PROMs at a minimum of 2 years follow up. Median IKDC, Lysholm, and Simple Knee Value were 82.8, 85.5, and 77.5, respectively. For the Tegner Activity Scale we recorded a median value of 8.0 before injury and 6.0 after surgery. Timing for return-to-play was between 6 and 9 months for 19 patients (54.3%). Regarding post-surgery complications, we recorded an overall rate of 15.79%, with however minor entity (Clavien-Dindo grade I). Allografts re-rupture rate was 10.5%.

CONCLUSION

BPTB allografts in one-stage ACL revision enabled patients to return to sports and to a good quality of life after the final follow up. Moreover, this type of graft has been shown to be a safe choice, being burdened by a low rate of post-surgical complications and re-rupture risk.

摘要

背景

前交叉韧带断裂是体育运动中最常见的损伤之一。尽管一期重建手术成功率较高,但据报道仍有高达13%的患者手术失败。对于主诉膝关节不稳的患者,应建议并与患者讨论进行翻修手术。在此情况下出现的问题是移植物的选择,由于一期手术已使用过的移植物,选择受到限制。

方法

我们回顾性纳入了38例连续接受单中心同种异体骨-髌腱-骨(BPTB)移植进行前交叉韧带一期翻修手术的患者,随访时间至少2年。临床评估基于患者报告结局量表(PROMs)。此外,我们记录了同种异体移植物再断裂率和术后并发症发生率。

结果

我们的系列研究显示,在至少2年的随访中,患者报告结局量表结果良好。国际膝关节文献委员会(IKDC)评分、Lysholm评分和简易膝关节评分的中位数分别为82.8、85.5和77.5。对于Tegner活动量表,我们记录到受伤前的中位数为8.0,术后为6.0。19例患者(54.3%)恢复运动的时间在6至9个月之间。关于术后并发症,我们记录的总体发生率为15.79%,但均为轻微情况(Clavien-Dindo分级I级)。同种异体移植物再断裂率为10.5%。

结论

在一期前交叉韧带翻修手术中使用BPTB同种异体移植物,能使患者在末次随访后恢复运动并拥有良好的生活质量。此外,这种类型的移植物已被证明是一种安全的选择,术后并发症发生率低,再断裂风险小。

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