Orthopedic Department, San Gerardo Hospital, Monza, Italy.
School of Medicine and Surgery, University of Milano-Bicocca, Via Pergolesi 33, 20900, Monza, Italy.
Eur J Orthop Surg Traumatol. 2023 Aug;33(6):2191-2199. doi: 10.1007/s00590-022-03402-z. Epub 2022 Oct 29.
Clinical outcomes and potential complications associated with Bone-Patellar Tendon-Bone (BPTB) graft in skeletally immature ACL reconstruction (ACLR) are poorly defined. Considering that in Tanner 1-2 patients this kind of graft is not recommended, we focused our systematic review on the evaluation of all the studies in the literature that reported clinical outcomes and rate of complications of the ACLR using BPTB graft in Tanner 3-4 patients.
This review was conducted in accordance with the PRISMA statement. PubMed, Cochrane Library, EMBASE and Scopus were examined from 1965 to 2020 using different combinations of the following keywords: "ACL reconstruction", "skeletally immature", "young", "patellar tendon" and "BPTB". The database search yielded 742 studies, on which we performed a primary evaluation. After carrying out a full-text evaluation for the inclusion criteria, 4 studies were included in the final review and assessed using the Newcastle-Ottawa scale. Ninety-six cases with mean age of 14.2 years were reported.
Good stability and functional outcomes were reported with a mean follow-up of 49.5 months. Return to sport rate ranged from 91.7% to 100%. A KT-1000 side-to-side difference higher than 5 mm was observed in five patients (5.2%). No lower limb length discrepancy and angulation were reported. Graft rupture rate was 5.2%.
According to these results, BTPB graft could be a good choice in Tanner 3-4 patients who want to achieve their preinjury sport level with a low risk of growth disturbances and graft failure. Further investigations in a wider population are needed.
在骨骼未成熟的前交叉韧带重建(ACLR)中,骨-髌腱-骨(BPTB)移植物的临床结果和潜在并发症定义不明确。鉴于在 Tanner 1-2 期患者中不推荐使用这种移植物,我们的系统评价重点关注评估文献中所有报告使用 BPTB 移植物在 Tanner 3-4 期患者中进行 ACLR 的临床结果和并发症发生率的研究。
本综述符合 PRISMA 声明。使用以下关键词的不同组合在 1965 年至 2020 年期间在 PubMed、Cochrane 图书馆、EMBASE 和 Scopus 中进行了检索:“ACL 重建”、“骨骼未成熟”、“年轻”、“髌腱”和“BPTB”。数据库搜索产生了 742 项研究,我们对这些研究进行了初步评估。在对纳入标准进行全文评估后,有 4 项研究被纳入最终综述,并使用纽卡斯尔-渥太华量表进行评估。报告了 96 例平均年龄为 14.2 岁的病例。
报告了良好的稳定性和功能结果,平均随访时间为 49.5 个月。重返运动率为 91.7%至 100%。在 5 名患者(5.2%)中观察到 KT-1000 侧-侧差值大于 5 毫米。未报告下肢长度差异和角度。移植物断裂率为 5.2%。
根据这些结果,BTPB 移植物可能是 Tanner 3-4 期患者的一个不错选择,他们希望以较低的生长障碍和移植物失败风险恢复到受伤前的运动水平。需要在更广泛的人群中进行进一步研究。