Jørgensen Mie Sedoc, Cano Kiana, Sharp Carla, Bo Sune, Storebø Ole Jakob, Vestergaard Martin, Møller Lise, Poulsen Stig, Beck Emma, Simonsen Erik
Psychiatric Research Unit, Region Zealand, Slagelse, Denmark.
Center for Eating and Feeding Disorders Research (CEDaR), Psychiatric Center Ballerup, Capital Region, Ballerup, Denmark.
Personal Ment Health. 2025 Aug;19(3):e70031. doi: 10.1002/pmh.70031.
Sleep disturbances are commonly reported in individuals with borderline personality disorder (BPD) and are often worsened by comorbid mental health disorders such as ADHD, PTSD, and depression. Sleep problems may contribute to the persistence of symptoms, highlighting the importance of early identification and treatment of sleep disturbances as part of early intervention strategies. Despite this, the prevalence and predictors of persistent sleep problems in the early course of BPD remain understudied, particularly in longitudinal designs. In this study, we followed up on 110 female adolescents with BPD pathology 5 years after being included in the study to investigate the prevalence and predictors of sleep problems collected using a semistructured interview as participants transitioned into early adulthood. At baseline, BPD severity, ADHD, and melatonin use were associated with sleep disturbances. However, at 5-year follow-up, baseline ADHD, depression severity, and melatonin use emerged as the strongest predictors of persistent sleep problems, while BPD severity was no longer predictive. These findings underscore the complex interplay between comorbid mental health disorders and the development and maintenance of sleep problems in BPD. Targeting adolescents with BPD and severe sleep disturbances requiring medical intervention, comorbid ADHD, and significant depressive symptoms is crucial for alleviating persistent sleep problems. Integrating specific sleep interventions into early treatment strategies represents sound clinical management in the early stages of BPD, and future research should explore whether targeted interventions for these risk factors can mitigate long-term sleep-related challenges and improve overall outcomes for individuals with BPD.
边缘型人格障碍(BPD)患者常报告有睡眠障碍,并且往往会因多动症(ADHD)、创伤后应激障碍(PTSD)和抑郁症等共病心理健康障碍而恶化。睡眠问题可能会导致症状持续存在,这凸显了作为早期干预策略的一部分,早期识别和治疗睡眠障碍的重要性。尽管如此,BPD早期持续存在睡眠问题的患病率和预测因素仍未得到充分研究,尤其是在纵向研究设计中。在本研究中,我们对110名患有BPD病理特征的女性青少年进行了随访,随访时间为她们被纳入研究后的5年,以调查在参与者进入成年早期时,通过半结构化访谈收集的睡眠问题的患病率和预测因素。在基线时,BPD严重程度、ADHD和褪黑素的使用与睡眠障碍有关。然而,在5年随访时,基线时的ADHD、抑郁严重程度和褪黑素的使用成为持续睡眠问题的最强预测因素,而BPD严重程度不再具有预测性。这些发现强调了共病心理健康障碍与BPD中睡眠问题的发生和维持之间的复杂相互作用。针对患有BPD且有严重睡眠障碍需要医学干预、共病ADHD和有明显抑郁症状的青少年,对于缓解持续睡眠问题至关重要。将特定的睡眠干预措施纳入早期治疗策略是BPD早期阶段合理的临床管理方法,未来的研究应探索针对这些风险因素的有针对性的干预措施是否可以减轻与睡眠相关的长期挑战,并改善BPD患者的整体预后。