Muhammad T, Mu Christina X, Srivastava Shobhit, Joseph Vinod Joseph Kannankeril, Drishti Drishti, Ali Waad, Zanwar Preeti Pushpalata
Department of Human Development and Family Studies| Center for Healthy Aging, Pennsylvania State University, University Park, PA, 16802, USA.
Department of Epidemiology and Biostatistics, University of California, San Francisco, USA.
Soc Psychiatry Psychiatr Epidemiol. 2025 Jun 27. doi: 10.1007/s00127-025-02950-z.
The death of a spouse is considered one of the most life challenging stressors. Widowhood has a profound influence on health and may increase the risk of depression and poorer cognitive function. Discriminatory practices in India, such as taboos against remarrying, a lack of occupational opportunities, and social support, may lead to differential widowhood experiences, especially among women. This study examined the associations between widowhood status/duration, depression and cognitive function among community-dwelling men and women in India. Considering the unique cultural and societal context in India, this study also sought to examine differences by sex, rural/urban residence, and multigenerational living status.
We used baseline data from the Longitudinal Aging Study in India. Data were collected between 2017 and 2019. The study sample consisted of 14,691 men and 15,948 women age ≥ 60 years. Depression was measured using the Short Form Composite International Diagnostic Interview and global cognitive functioning was measured using an assessment adapted from the Mini-Mental State Examination and the cognitive module of the United States Health and Retirement Study, and its sister studies. We employed adjusted multivariable logistic and linear regression models to examine the association of widowhood status/duration with the risk of depression, and cognitive function.
Compared to currently married, those widowed within 0-9 years had a higher risk of depression (Men: aOR = 1.65, 95% CI: 1.20, 2.27; Women: aOR = 1.57, 95% CI = 1.25, 1.98) and worse cognitive functioning (Men: B = 0.80, 95% CI: 0.30, 1.30; Women: B = 0.55, 95% CI = 0.20, 0.91). Among those widowed within 0-9 years, men had a slightly greater risk of worse cognitive functioning than women. As widowhood duration increased, the association between widowhood and worse cognitive functioning was no longer significant among men but remained significant among women. Analyses stratified by rural/urban residence and multigenerational living status and their interactions with widowhood status/duration revealed similar trends. However, the associations between widowhood status/duration and worse cognitive function were more pronounced among women in non-multigenerational households (interaction p <.05).
Older adults who were widowed within 0-9 years had a higher risk of depression and worse cognitive functioning. The adverse effects of widowhood on cognition were no longer significant among men but persisted for women with longer widowhood duration. Non-multigenerational households exacerbated the influence of widowhood on the higher risk of depression and worse cognitive functioning, but findings by urban/rural residence were mixed. Future research should explore what other factors moderate widowhood and health relations and examine changes in widowhood duration over time.
配偶死亡被认为是最具生活挑战性的压力源之一。丧偶对健康有深远影响,可能会增加患抑郁症和认知功能下降的风险。印度的歧视性做法,如再婚禁忌、缺乏职业机会和社会支持,可能导致不同的丧偶经历,尤其是在女性中。本研究调查了印度社区居住的男性和女性丧偶状况/持续时间、抑郁症和认知功能之间的关联。考虑到印度独特的文化和社会背景,本研究还试图按性别、城乡居住情况和多代同堂居住状况来考察差异。
我们使用了来自印度纵向老龄化研究的基线数据。数据收集于2017年至2019年之间。研究样本包括14691名年龄≥60岁的男性和15948名年龄≥60岁的女性。使用简短版综合国际诊断访谈来测量抑郁症,使用改编自简易精神状态检查表和美国健康与退休研究及其姊妹研究的认知模块的评估方法来测量整体认知功能。我们采用调整后的多变量逻辑回归和线性回归模型来研究丧偶状况/持续时间与抑郁症风险和认知功能之间的关联。
与目前已婚者相比,在0至9年内丧偶的人患抑郁症的风险更高(男性:调整后的比值比[aOR]=1.65,95%置信区间[CI]:1.20,2.27;女性:aOR=1.57,95%CI=1.25,1.98),认知功能也更差(男性:B=0.80,95%CI:0.30,1.30;女性:B=0.55,95%CI=0.20,0.9)。在0至9年内丧偶的人中,男性认知功能变差的风险略高于女性。随着丧偶持续时间的增加,丧偶与认知功能变差之间的关联在男性中不再显著,但在女性中仍然显著。按城乡居住情况和多代同堂居住状况及其与丧偶状况/持续时间的相互作用进行分层分析,结果显示了类似的趋势。然而,在非多代同堂家庭的女性中,丧偶状况/持续时间与认知功能变差之间的关联更为明显(交互作用p<0.05)。
在0至9年内丧偶的老年人患抑郁症的风险更高,认知功能也更差。丧偶对认知的不利影响在男性中不再显著,但在丧偶持续时间较长的女性中仍然存在。非多代同堂家庭加剧了丧偶对患抑郁症风险更高和认知功能更差的影响,但城乡居住情况的研究结果不一。未来的研究应探索还有哪些其他因素调节丧偶与健康之间的关系,并研究丧偶持续时间随时间的变化。