Prasad Rajeshwari Kebbepura Mahadeva, Chidananda Shubhada Handly, Shivanand Bindya, Basavarajappa Hemavathi Ajjipura, Shivamallu Chandan, Chandraiah Revanth Handralu, Dharmashekar Chandan, Kollur Shiva Prasad
Department of Chemistry, SJCE, JSS Science and Technology University, Mysuru 570 006, Karnataka, India.
Department of Chemistry, SJCE, JSS Science and Technology University, Mysuru 570 006, Karnataka, India.
Int J Biol Macromol. 2025 Aug;319(Pt 3):145595. doi: 10.1016/j.ijbiomac.2025.145595. Epub 2025 Jun 26.
In the present study, poly (vinyl alcohol) (PVA), kappa-Carrageenan (kC), kC/PVA polymer blend and kC/PVA nanocomposites incorporating varying concentrations of TiO₂ nanoparticles (1 %, 1.5 %, 2 %, and 2.5 % w/w) were successfully prepared and characterized for its electrical, optical and biological behaviour. The composite film was prepared using a solution casting method by incorporating titanium dioxide (TiO₂) nanoparticles into polymer matrix to enhance its multifunctional properties. The mechanical, structural, morphological, thermal, electrical and optical characteristics of the films were systematically analysed using various techniques. XRD analysis confirmed the effective incorporation of TiO₂ nanoparticles into the polymer matrix, resulting in improved crystallinity. FTIR spectra indicated strong chemical interactions between the polymer blend and nanoparticles, suggesting enhanced compatibility and uniform dispersion. The mechanical properties of the nanocomposite were notably improved with filler incorporation. UV-Visible spectroscopy revealed increased optical absorption upon nanoparticle addition, while a noticeable reduction in optical band gap pointed to enhanced optoelectronic characteristics. Electrical measurements showed a significant rise in AC conductivity, correlating with efficient charge transport due to well-dispersed nanoparticles. Dielectric studies supported these findings, showing enhanced dielectric behaviour at optimal nanoparticle concentration, demonstrating potential for energy-related applications. The nanocomposite film showed significant antimicrobial activity against both gram-negative (E. coli) and gram-positive (S. aureus) bacteria, along with enhanced wound healing behaviour, highlighting its potential as a promising material for biomedical applications. The synergistic effect of TiO₂ in kC/PVA matrix resulted in a polymer nanocomposite film with enhanced mechanical strength, AC conductivity, optical responsiveness and biological activity.
在本研究中，成功制备了聚乙烯醇（PVA）、κ-卡拉胶（kC）、kC/PVA聚合物共混物以及包含不同浓度二氧化钛纳米颗粒（1%、1.5%、2%和2.5% w/w）的kC/PVA纳米复合材料，并对其电学、光学和生物学行为进行了表征。通过将二氧化钛（TiO₂）纳米颗粒掺入聚合物基质中，采用溶液浇铸法制备了复合薄膜，以增强其多功能性能。使用各种技术系统地分析了薄膜的机械、结构、形态、热学、电学和光学特性。XRD分析证实了TiO₂纳米颗粒有效掺入聚合物基质中，从而提高了结晶度。FTIR光谱表明聚合物共混物与纳米颗粒之间存在强烈的化学相互作用，表明相容性增强且分散均匀。随着填料的掺入，纳米复合材料的机械性能显著提高。紫外-可见光谱显示添加纳米颗粒后光吸收增加，而光学带隙的显著降低表明光电特性增强。电学测量显示交流电导率显著提高，这与由于纳米颗粒分散良好而实现的有效电荷传输相关。介电研究支持了这些发现，表明在最佳纳米颗粒浓度下介电行为增强，展示了其在能源相关应用中的潜力。纳米复合薄膜对革兰氏阴性菌（大肠杆菌）和革兰氏阳性菌（金黄色葡萄球菌）均表现出显著的抗菌活性，同时伤口愈合行为增强，突出了其作为生物医学应用中有前景材料的潜力。TiO₂在kC/PVA基质中的协同作用产生了一种具有增强机械强度、交流电导率、光学响应性和生物活性的聚合物纳米复合薄膜。
