Ahmed M, Siddique M A, Islam M M, Nuruzzaman M, Alam M M, Khan M J A
Dr Miraj Ahmed, Assistant Professor, Department of ENT & Head-Neck Surgery, Mymensingh Medical College (MMC), Bangladesh; E-mail:
Mymensingh Med J. 2025 Jul;34(3):656-659.
Total thyroidectomy is a common surgical procedure for MNG and thyroid malignancies with or without lymph node metastasis. Post total thyroidectomy hypoparathyroidism is not so uncommon. Understanding the prevalence of temporary and permanent hypoparathyroidism in post-total thyroidectomy is very important for improving patient outcomes. This prospective observational study was conducted in Mymensingh Medical College Hospital, Mymensingh, Bangladesh from January 2023 to December 2023 where 92 cases were selected purposively who underwent total thyroidectomy for MNG and thyroid malignancy without extra thyroidal extension. The incidence of transient and permanent hypoparathyroidism after total thyroidectomy, demographic variables, and postoperative day of onset of hypocalcemia were analyzed. Data collection was done through patient records and postoperative follow-ups. This study revealed that 23.0% of patients experienced hypoparathyroidism post-operatively. Hypoparathyroidism was most prevalent among patients underwent total thyroidectomy for thyroid malignancy (47.83%) compared to those undergoing total thyroidectomy for benign thyroid disease (17.39%). The majority of hypocalcemia cases (60.87%) occurred on the second postoperative day. Among the 23 cases of postoperative hypoparathyroidism temporary hypoparathyroidism was 69.57% and permanent hypoparathyroidism was 30.43%. After total thyroidectomy Hypoparathyroidism remains a significant complication. Early identification and management of at-risk patients is necessary to reduce the severity of this complication.
全甲状腺切除术是治疗多结节性甲状腺肿（MNG）及有无淋巴结转移的甲状腺恶性肿瘤的常见外科手术。全甲状腺切除术后甲状旁腺功能减退并不罕见。了解全甲状腺切除术后暂时性和永久性甲状旁腺功能减退的发生率对于改善患者预后非常重要。这项前瞻性观察性研究于2023年1月至2023年12月在孟加拉国迈门辛的迈门辛医学院医院进行，选取了92例因多结节性甲状腺肿和甲状腺恶性肿瘤而接受全甲状腺切除术且无甲状腺外侵犯的患者。分析了全甲状腺切除术后暂时性和永久性甲状旁腺功能减退的发生率、人口统计学变量以及低钙血症发作的术后天数。通过患者记录和术后随访进行数据收集。该研究表明，23.0%的患者术后出现甲状旁腺功能减退。与因良性甲状腺疾病接受全甲状腺切除术的患者（17.39%）相比，因甲状腺恶性肿瘤接受全甲状腺切除术的患者中甲状旁腺功能减退最为普遍（47.83%）。大多数低钙血症病例（60.87%）发生在术后第二天。在23例术后甲状旁腺功能减退病例中，暂时性甲状旁腺功能减退占69.57%，永久性甲状旁腺功能减退占30.43%。全甲状腺切除术后甲状旁腺功能减退仍然是一种严重的并发症。早期识别和管理高危患者对于降低该并发症的严重程度是必要的。
