Sevindik Serkan, Erol Kemal, Levendoğlu Funda, Gezer Ilknur Albayrak
Department of Physical Medicine and Rehabilitation, Department of Physical Medicine and Rehabilitation, Selçuk University Faculty of Medicine, Konya, Türkiye.
Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Selçuk University Faculty of Medicine, Konya, Türkiye.
J Rheum Dis. 2025 Jul 1;32(3):190-197. doi: 10.4078/jrd.2025.0013. Epub 2025 Apr 30.
The aim of this study was to evaluate the prevelance of lumbosacral transitional vertebrae (LSTV) in patients with axial spondyloarthritis (ax-SpA), and to explore the relationship of the presence of LSTV with the burden of disease.
A total of 177 patients classified with ax-SpA according to ASAS (Assessment of Spondyloarthritis International Society) criteria who were admitted to Selçuk University Medical Faculty rheumatology outpatient clinic were included, consecutively. Demographic, clinical, and laboratory data were recorded. LSTV was evaluated on AnteroPosterior (AP) pelvic radiographs and AP lumbar radiographs according to the Castellvi classification.
Of 177 patients with axSpA, 99 (55.9%) were radiographic axSpA (r-axSpA). LSTV was detected in 51 (28.8%) patients with ax-SpA (with the frequency of 32.3% in r-axSpA and 24.4% in non-r-axSpA [nr-axSpA] [p>0.05]). Most frequent LSTV subtype was type 1 (32 of 51 [62.7%]). Thirty-two (62.7%) of 51 patients with LSTV were r-axSpA, and 19 (37.3%) patients with LSTV were nr-axSpA (p=0.245). The demographic characteristics of the group with and without LSTV were similar. There was no significant difference in terms of VAS, BASDAI, BASFI, ASDAS-CRP, BASMI, HAQ, EQ-5D-3L scores and no difference in disease activity in terms of presence of LSTV in patients with ax-SpA.
The prevalence of LSTV in patients with ax-SpA was 28.8%, consistent with some population based studies in the literature. There was no difference between patients with and without LSTV in terms of burden of disease in patients with ax-SpA.
本研究旨在评估轴向性脊柱关节炎（ax-SpA）患者腰骶部移行椎（LSTV）的患病率，并探讨LSTV的存在与疾病负担之间的关系。
连续纳入塞尔丘克大学医学院风湿病门诊收治的、根据国际脊柱关节炎评估协会（ASAS）标准分类为ax-SpA的177例患者。记录人口统计学、临床和实验室数据。根据Castellvi分类法，在前后位（AP）骨盆X线片和AP腰椎X线片上评估LSTV。
177例ax-SpA患者中，99例（55.9%）为放射学ax-SpA（r-axSpA）。在51例（28.8%）ax-SpA患者中检测到LSTV（r-axSpA中为32.3%，非r-axSpA [nr-axSpA]中为24.4% [p>0.05]）。最常见的LSTV亚型为1型（51例中的32例[62.7%]）。51例LSTV患者中，32例（62.7%）为r-axSpA，19例（37.3%）为nr-axSpA（p=0.245）。有LSTV组和无LSTV组的人口统计学特征相似。ax-SpA患者中，有无LSTV在视觉模拟评分（VAS）、巴斯强直性脊柱炎疾病活动指数（BASDAI）、巴斯强直性脊柱炎功能指数（BASFI）、强直性脊柱炎疾病活动评分（ASDAS-CRP）、巴斯强直性脊柱炎脊柱活动度指数（BASMI）、健康评估问卷（HAQ）、欧洲五维度健康量表（EQ-5D-3L）评分方面无显著差异，疾病活动度也无差异。
ax-SpA患者中LSTV的患病率为28.8%，与文献中一些基于人群的研究结果一致。ax-SpA患者中，有无LSTV在疾病负担方面无差异。
