Miladi Qonita Nur, Pahria Tuti, Pramukti Iqbal
Master Study Program, Faculty of Nursing, Universitas Padjadjaran, Sumedang, West Java, Indonesia.
Department of Medical-Surgical Nursing, Faculty of Nursing, Universitas Padjadjaran, Sumedang, West Java, Indonesia.
Patient Prefer Adherence. 2025 Jun 23;19:1807-1823. doi: 10.2147/PPA.S533210. eCollection 2025.
Pulmonary tuberculosis (TB) remains a global health concern with high morbidity and mortality rates. Despite being curable with proper treatment, challenges in ensuring continuity of care persist, particularly in resource-limited settings. Digital health interventions (DHI) offer a potential solution to improve treatment adherence and continuity of care among TB patients.
This study aimed to systematically review how DHIs contribute to improved continuity of care, particularly in terms of medication adherence, clinical outcomes, and patient satisfaction.
A systematic review was conducted using PRISMA guidelines. Relevant studies were identified from five significant databases, including PubMed, Scopus, Taylor and Francis, EBSCO-host, and ScienceDirect, up to November 2024 and one search engine was Google Scholar. The keywords used were "pulmonary tuberculosis OR tbc OR tb AND mobile health applications OR mhealth OR mobile apps OR telehealth AND continuity of care OR patient compliance OR patient adherence OR adherence behaviour. Inclusion criteria focused on RCTs evaluating DHIs for adult TB patients. Data were extracted and analyzed thematically to assess intervention effectiveness on medication adherence and clinical outcomes.
A total of 17.380 patients from 21 studies TB patients were included. Interventions were classified into two categories: reminder-based (eg, SMS, phone calls, electronic medicine boxes with audio/visual alerts) and remote monitoring-based (eg, MERM, mobile applications, digital sensors, and VDOT). Compared to standard care, DHIs significantly improved medication adherence, treatment success rates, and patient satisfaction. Several studies also reported reduced time and cost burdens for patients.
DHIs improve continuity of care among TB patients by increasing medication adherence and clinical outcomes. However, the effectiveness varies across different intervention types and settings, emphasizing the need for tailored strategies and integration into existing health systems.
肺结核（TB）仍然是一个全球健康问题，发病率和死亡率都很高。尽管通过适当治疗可以治愈，但在确保持续护理方面仍存在挑战，特别是在资源有限的环境中。数字健康干预措施（DHI）为提高结核病患者的治疗依从性和持续护理提供了一种潜在的解决方案。
本研究旨在系统评价数字健康干预措施如何有助于改善持续护理，特别是在药物依从性、临床结局和患者满意度方面。
使用PRISMA指南进行系统评价。从五个重要数据库中识别相关研究，包括PubMed、Scopus、Taylor and Francis、EBSCO-host和ScienceDirect，截至2024年11月，还有一个搜索引擎是谷歌学术。使用的关键词是“肺结核或结核病或tb与移动健康应用程序或移动医疗或移动应用或远程医疗以及持续护理或患者依从性或患者坚持或坚持行为”。纳入标准侧重于评估针对成年结核病患者的数字健康干预措施的随机对照试验。提取数据并进行主题分析，以评估干预措施对药物依从性和临床结局的有效性。
纳入了来自21项研究的总共17380名结核病患者。干预措施分为两类：基于提醒的（如短信、电话、带有音频/视觉警报的电子药盒）和基于远程监测的（如移动电子远程监测、移动应用程序、数字传感器和视频直接观察疗法）。与标准护理相比，数字健康干预措施显著提高了药物依从性、治疗成功率和患者满意度。几项研究还报告说，患者的时间和成本负担有所减轻。
数字健康干预措施通过提高药物依从性和临床结局来改善结核病患者的持续护理。然而，不同干预类型和环境的有效性各不相同，这强调了需要制定量身定制的策略并将其纳入现有的卫生系统。
