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双阻板矫治器对Ⅱ类错合伴下颌后缩阻塞性睡眠呼吸暂停低通气综合征儿童生活质量的影响

Effects of twin-block appliance on quality of life in OSA children with class 2 malocclusion and mandibular retrognathia.

作者信息

Zreaqat Maen, Alforaidi Sahal, Hassan Rozita

机构信息

Orthodontic Dep. School of Dental Sciences, Universiti Sains Malaysia, Malaysia.

Pediatric Dentistry and and Orthodontics Dep. College of Dentistry, Taiba University, Saudi Arabia.

出版信息

J Oral Biol Craniofac Res. 2025 Jul-Aug;15(4):864-868. doi: 10.1016/j.jobcr.2025.06.003. Epub 2025 Jun 13.

DOI:10.1016/j.jobcr.2025.06.003
PMID:40586105
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12205320/
Abstract

PURPOSE

Twin block has been proposed as a potential oral appliance for the treatment of obstructive sleep apnea (OSA) in children with class 2 skeletal malocclusion. This study aimed to evaluate the impact of twin block appliance on quality of life in children with OSA.

MATERIALS AND METHODS

This case series study comprised 47 growing OSA children with Class 2 skeletal malocclusion and mandibular retrognathia aged 10-12 years. Patients were treated with a functional twin block appliance and the quality of life was assessed using the OSA-18 questionnaire, which was administered before appliance insertion and 30 days after the end of treatment. Additionally, a second standard overnight polysomnography (PSG) was performed to determine changes in respiratory parameters.

RESULTS

All domains of the OSA-18 questionnaire showed significant changes (P < 0.025), except for physical suffering domain (P = 0.075). The mean total scores of the OSA-18 questionnaire decreased from 81.55 to and 53.07 scores (28.49 scores, P < 0.001). At the end of the treatment, the apnea-hypopnea index decreased significantly by 4.53 events/h (74.0 %), P < 0.001).

CONCLUSION

The twin block appliance resulted in a significant improvement in four of the five domains of the OSA-18 questionnaire, with a positive impact on the quality of life in OSA children with Class 2 skeletal malocclusion. Patients showed significant improvements in respiratory sleep parameters and parent-reported symptoms.

摘要

目的

双阻板矫治器已被提议作为治疗安氏II类骨性错牙合儿童阻塞性睡眠呼吸暂停(OSA)的一种潜在口腔矫治器。本研究旨在评估双阻板矫治器对OSA儿童生活质量的影响。

材料与方法

本病例系列研究纳入了47名年龄在10 - 12岁、患有安氏II类骨性错牙合和下颌后缩的生长发育期OSA儿童。患者接受功能性双阻板矫治器治疗,并使用OSA - 18问卷评估生活质量,该问卷在矫治器佩戴前及治疗结束后30天进行发放。此外,进行了第二次标准的夜间多导睡眠图(PSG)检查以确定呼吸参数的变化。

结果

除身体痛苦领域外(P = 0.075),OSA - 18问卷的所有领域均显示出显著变化(P < 0.025)。OSA - 18问卷的平均总分从81.55分降至53.07分(降低28.49分,P < 0.001)。治疗结束时,呼吸暂停低通气指数显著降低4.53次/小时(74.0%),P < 0.001)。

结论

双阻板矫治器使OSA - 18问卷五个领域中的四个领域有显著改善,对安氏II类骨性错牙合的OSA儿童生活质量产生了积极影响。患者的呼吸睡眠参数和家长报告的症状有显著改善。

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Effects of Twin-Block Appliance Therapy on Urinary Leukotriene E4 and Serum C-Reactive Protein Levels in Obstructive Sleep Apnea Children with Class II Malocclusion and Mandibular Retrognathia: A Prospective Longitudinal Study.双阻板矫治器治疗对伴有安氏II类错合及下颌后缩的阻塞性睡眠呼吸暂停儿童尿白三烯E4和血清C反应蛋白水平的影响:一项前瞻性纵向研究
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