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[成人急性小脑脑炎]

[Acute cerebellar encephalitis in adulthood].

作者信息

Kömpf D, Engelhardt A, Dietrich H J, Neundörfer B

出版信息

Nervenarzt. 1985 Aug;56(8):431-9.

PMID:4058617
Abstract

Two cases of rare adult cerebellar encephalitis are reported presenting the distinguishing features of acute onset of cerebellar ataxia, distinct ocular oscillations (opsoclonus, ocular flutter, macro square wave jerks) and generalized myoclonic jerks. The EOG-analysis of the cerebellar oculomotor disorder is emphasized. The course is usually benign ("benign encephalitis") differing from the childhood form only in age of onset. Fatal courses are rare and the histopathologic findings in one case suggest mild encephalitis with diffuse perivascular lesions accentuated in the cerebellum, thus not allowing clear clinicotopodiagnostic correlations.

摘要

报告了两例罕见的成人小脑性脑炎病例,其特征为急性小脑共济失调、明显的眼球震颤(眼阵挛、眼球扑动、巨大方波急跳)和全身性肌阵挛急跳。着重介绍了小脑动眼障碍的眼电图分析。病程通常为良性(“良性脑炎”),仅发病年龄与儿童型不同。致命病程罕见,一例的组织病理学发现提示为轻度脑炎,伴有弥漫性血管周围病变,在小脑中更为明显,因此无法进行明确的临床-拓扑诊断关联。

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