Yang C, Ma G J, Zhou X C, Qin A S, Qi X, Liu B
Department of Burn, Plastic and Cosmetic Surgery, Xi'an Central Hospital, Xi'an Jiaotong University, Xi'an 710003, China.
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2025 Jun 20;41(6):552-558. doi: 10.3760/cma.j.cn501225-20241209-00481.
To evaluate the application efficacy of lymph pads in complete decongestive therapy after lymphatico-venous anastomosis (LVA) combined with liposuction in patients with lower limb lymphedema. This study was a historical control study. From June 2021 to January 2023, a total of 23 patients who underwent LVA combined with liposuction and then complete decongestive therapy without application of lymph pads at the Department of Burn, Plastic and Cosmetic Surgery of Xi'an Central Hospital of Xi'an Jiaotong University (hereinafter referred to as our department) were included as control group. There were 2 males and 21 females in this group, with the age of 58±10 years. From February 2023 to January 2024, another 23 patients who underwent LVA combined with liposuction and then complete decongestive therapy with additional application of lymph pads at our department were included as lymph pad group. There were 3 males and 20 females in this group, with the age of 59±11 years. Before treatment and at 6 and 12 months of treatment, the circumferences of the dorsum of the foot, ankle joint, and upper edge of the knee joint of the affected limbs were measured, and the total score of lymphedema functioning, disability and health questionnaire for lower limb lymphedema (Lymph-ICF-LL) and score of lower limb function in Lymph-ICF-LL were recorded in patients in the two groups. At 6 and 12 months of treatment, the circumferences of the dorsum of the foot, ankle joint, and upper edge of the knee joint in patients in lymph pad group were (22.9±1.7), (26±3), (44±8) cm and (20.7±1.7), (25±3), (42±6) cm, respectively, which were significantly smaller than (24.3±2.3), (29±4), (49±10) cm and (23.9±2.2), (29±4), (48±12) cm in control group (with values of 2.18, 2.29, 2.09, and 5.84, 3.92, 2.31, respectively, <0.05), and the mean differences (95% confidence intervals) between the two groups were 1.3 (0.1 to 2.5), 2 (0 to 4), 5 (0 to 10) cm and 3.3 (2.2 to 4.5), 4 (2 to 6), 6 (1 to 12) cm, respectively. There were no statistically significant differences in the total Lymph-ICF-LL scores of the affected limbs between the two groups of patients before treatment and at 6 and 12 months of treatment (>0.05). At 6 and 12 months of treatment, the lower limb function scores in Lymph-ICF-LL of the affected limbs in lymph pad group of patients were significantly lower than those in control group (with values of 2.24 and 2.44, respectively, <0.05), and the mean differences (95% confidence intervals) between the two groups were 5 (1 to 9) and 5 (1 to 9) cm, respectively. During complete decongestive therapy following LVA combined with liposuction, the application of lymph pads can significantly reduce the circumference of the dorsum of the foot, ankle joint, and knee joint in patients with lower limb lymphedema, and also improve their lower limb function.
评估淋巴垫在下肢淋巴水肿患者行淋巴管静脉吻合术(LVA)联合抽脂术后完全减压治疗中的应用效果。本研究为历史性对照研究。2021年6月至2023年1月,西安交通大学附属西安中心医院烧伤整形美容外科(以下简称我科)共纳入23例行LVA联合抽脂术,随后未使用淋巴垫进行完全减压治疗的患者作为对照组。该组有男性2例,女性21例,年龄58±10岁。2023年2月至2024年1月,我科另纳入23例行LVA联合抽脂术,随后使用淋巴垫进行完全减压治疗的患者作为淋巴垫组。该组有男性3例,女性20例,年龄59±11岁。在治疗前以及治疗6个月和12个月时,测量患侧肢体足背、踝关节及膝关节上缘的周径,并记录两组患者下肢淋巴水肿功能、残疾和健康问卷(Lymph-ICF-LL)的总分以及Lymph-ICF-LL中下肢功能评分。治疗6个月和12个月时,淋巴垫组患者足背、踝关节及膝关节上缘的周径分别为(22.9±1.7)、(26±3)、(44±8)cm和(20.7±1.7)、(25±3)、(42±6)cm,显著小于对照组的(24.3±2.3)、(29±4)、(49±10)cm和(23.9±2.2)、(29±4)、(48±12)cm(t值分别为2.18、2.29、2.09以及5.84、3.92、2.31,均<0.05),两组间的平均差值(95%置信区间)分别为1.3(0.1至2.5)、2(0至4)、5(0至10)cm和3.3(2.2至4.5)、4(2至6)、6(1至12)cm。两组患者治疗前以及治疗6个月和12个月时患侧肢体Lymph-ICF-LL总分比较,差异均无统计学意义(>0.05)。治疗6个月和l2个月时,淋巴垫组患者患侧肢体Lymph-ICF-LL中下肢功能评分显著低于对照组(t值分别为2.24和2.44,均<0.05),两组间的平均差值(95%置信区间)分别为5(1至9)和5(1至9)cm。在LVA联合抽脂术后的完全减压治疗中,使用淋巴垫可显著减小下肢淋巴水肿患者的足背、踝关节及膝关节周径,还可改善其下肢功能。