Zhao Z Y, Cai C H, Liu H, Liu S W, Wang X G
Department of Burns and Wound Repair, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China.
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2025 Jun 20;41(6):604-608. doi: 10.3760/cma.j.cn501225-20241117-00448.
Wound healing is a complex biological process involving multiple stages, including hemostasis, inflammation, proliferation, and remodeling. Cold atmospheric plasma (CAP), as an efficient, non-invasive, and innovative therapy for wound care, has significant application prospects in this field. It has been demonstrated that CAP can promote wound cell proliferation and reduce microbial load on wounds through various mechanisms. Through a comprehensive analysis of recent domestic and international literature on the biological effects of CAP, this paper reviews how CAP promotes the repair of acute and chronic wounds from the perspectives of mechanism and clinical application and the research progress in the application methods of CAP in recent years.
伤口愈合是一个复杂的生物学过程，涉及多个阶段，包括止血、炎症、增殖和重塑。冷大气等离子体（CAP）作为一种高效、无创且创新的伤口护理疗法，在该领域具有显著的应用前景。已经证明，CAP可通过多种机制促进伤口细胞增殖并减少伤口上的微生物负荷。通过对近期国内外关于CAP生物学效应的文献进行综合分析，本文从机制和临床应用的角度综述了CAP如何促进急性和慢性伤口的修复以及近年来CAP应用方法的研究进展。
