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[碘化钾在离体兔眼中的摄取及其作为抗氧化剂的作用]

[The uptake of potassium iodide and its effect as an antioxidant in isolated rabbit eyes].

作者信息

Elstner E F, Adamczyk R, Kröner R, Furch A

出版信息

Ophthalmologica. 1985;191(2):122-6. doi: 10.1159/000309572.

Abstract

Potassium iodide (KI) passes the cornea of isolated rabbit eyes with kinetics of approximately 0.25 mumol/h/ml aqueous humor. In photodynamic reactions, simulated as light-dependent decay of S-methyl-alpha-ketobutyric acid in the presence of riboflavin, KI acts as an antioxidant cooperating with internal scavengers such as ascorbate. With the simple model reactions applied it may be possible to study mechanism and functions in vivo of eye-protecting factors or combinations of compounds.

摘要

碘化钾(KI)以约0.25微摩尔/小时/毫升房水的动力学通过离体兔眼的角膜。在光动力反应中,模拟为在核黄素存在下S-甲基-α-酮丁酸的光依赖性衰减,KI作为抗氧化剂与内部清除剂如抗坏血酸协同作用。应用简单的模型反应可能有助于研究眼保护因子或化合物组合在体内的机制和功能。

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