术前全口菌斑评分与下颌第三磨牙手术中的炎症并发症有关吗?队列研究。
Is pre-operative full mouth plaque score related to inflammatory complications in lower third molar surgery? cohort study.
作者信息
Roberto Pippi, Luisa Lauteri Maria, Stefano Petti
机构信息
Department of Odontostomatological and Maxillo Facial Sciences, Sapienza University of Rome, Rome, Italy.
, Private practice, Rome, Italy.
出版信息
Clin Oral Investig. 2025 Jul 1;29(7):364. doi: 10.1007/s00784-025-06442-x.
OBJECTIVES
The aim of this study was to investigate the association between pre-operative oral hygiene status and the occurrence of infectious-inflammatory complications, perceived pain, and swelling after lower third molar surgical extraction. Since oral hygiene is a modifiable factor, this study could provide suggestions to improve the success rate of third molar surgery.
MATERIALS AND METHODS
A cohort study was designed including two hundred twenty-two surgeries performed in adult patients. Full mouth plaque score (FMPS), as a parameter for oral hygiene status, demographic, anatomic and surgical variables were considered as predictor variables. Postoperative inflammatory complications, pain, swelling, and use of antibiotics were considered as study outcomes. The Common Factor Analysis was used to obtain a smaller set of new and not intercorrelated variables. A series of logistic regression analyses were used to assess the association between FMPS and the outcome variables.
RESULTS
FMPS was found independently associated with post-operative inflammatory complications, significantly, if treated as continuous variable, and marginally if treated as binary variable (threshold ≤ 20%/>20%). The association between FMPS and postoperative pain depended on the surgical complexity and was marginal if the score was treated as continuous variable, and significant if treated as binary variable. FMPS was found independently associated with postoperative antibiotic use if treated as continuous variable and not associated if treated as binary variable. An independent association between FMPS and postoperative swelling was found if the score was treated as continuous variable, while the association depended on sex if the score was treated as binary variable.
CONCLUSIONS
FMPS has a predictive role in the occurrence of post-operative inflammatory complications and post-surgical related symptoms and signs after lower third molar surgery.
CLINICAL RELEVANCE
It seems appropriate to evaluate the pre-operative FMPS to estimate the risk of patient discomfort and inflammatory complications in the post-operative period. Assuming that FMPS is causally associated with complications, in patients with high FMPS, it would be advisable to reschedule the surgery and perform a further pre-operative oral hygiene session to improve overall treatment outcomes and reduce the need for antibiotic use.
目的
本研究旨在调查术前口腔卫生状况与下颌第三磨牙拔除术后感染性炎症并发症、疼痛感知及肿胀情况之间的关联。由于口腔卫生是一个可改变的因素,本研究可为提高第三磨牙手术成功率提供建议。
材料与方法
设计一项队列研究,纳入对成年患者进行的222例手术。将全口菌斑评分(FMPS)作为口腔卫生状况的参数,人口统计学、解剖学和手术变量作为预测变量。术后炎症并发症、疼痛、肿胀及抗生素使用情况作为研究结果。采用共同因子分析以获得一组更小的、互不相关的新变量。一系列逻辑回归分析用于评估FMPS与结果变量之间的关联。
结果
发现FMPS与术后炎症并发症独立相关,若将其视为连续变量则具有显著相关性,若视为二元变量则相关性较弱(阈值≤20%/>20%)。FMPS与术后疼痛之间的关联取决于手术复杂性,若将评分视为连续变量则相关性较弱,若视为二元变量则具有显著相关性。若将FMPS视为连续变量,发现其与术后抗生素使用独立相关,若视为二元变量则无相关性。若将评分视为连续变量,发现FMPS与术后肿胀独立相关,若视为二元变量则该关联取决于性别。
结论
FMPS在下颌第三磨牙手术后的术后炎症并发症及术后相关症状和体征的发生中具有预测作用。
临床意义
评估术前FMPS以估计患者术后不适和炎症并发症的风险似乎是合适的。假设FMPS与并发症存在因果关联,对于FMPS较高的患者,建议重新安排手术时间并进行进一步的术前口腔卫生护理,以改善整体治疗效果并减少抗生素使用需求。