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创伤中心指定是否会影响烧伤患者的管理、并发症及治疗结果?一项国家创伤数据库分析。

Does trauma center designation impact management, complications, and outcomes in burn patients? A National Trauma Data Bank analysis.

作者信息

Stanton Eloise W, Manasyan Artur, Donohue Sean, Gillenwater Justin, Martin Mathew, Inaba Kenji, Yenikomshian Haig A

机构信息

Division of Plastic and Reconstructive Surgery, Keck School of Medicine, Los Angeles, CA, USA.

Division of Plastic and Reconstructive Surgery, Keck School of Medicine, Los Angeles, CA, USA; Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

出版信息

Burns. 2025 Sep;51(7):107588. doi: 10.1016/j.burns.2025.107588. Epub 2025 Jun 24.

Abstract

BACKGROUND

Burn injuries, particularly those involving large total body surface area (TBSA), present significant challenges due to fluid shifts, increased metabolic demands, and heightened susceptibility to complications. Trauma center designation, ranging from Level 1 (highest acuity) to Level 3, reflects differences in resources, expertise, and care protocols, which may influence patient outcomes. This study evaluates the impact of trauma center designation on transfusion practices, complications, and mortality among burn patients.

METHODS

The Trauma Quality Improvement Program (TQIP) database (2017-2022) was queried to identify burn patients by ICD-9/10 codes. Patients were categorized based on trauma center designation: Level 1 versus non-Level 1 (Levels 2 and 3). Outcomes analyzed included transfusion practices (e.g., packed red blood cells, plasma, platelets), inpatient complications, and mortality. Multivariable logistic regression was performed, adjusted for age, gender, %TBSA, inhalation injury, and Injury Severity Score (ISS). Subgroup analysis was performed for patients with burns > 20 % TBSA.

RESULTS

Among 72,474 burn patients, 47 % were treated at Level 1 centers. Patients at Level 1 centers presented with higher injury severity and had significantly higher rates of complications, including respiratory failure, sepsis, and surgical site infections. Despite the higher complication rates, Level 1 centers demonstrated significantly lower mortality compared to non-Level 1 centers (adjusted OR=0.46, 95 % CI 0.25-0.83, p = 0.011). Transfusion practices did not differ significantly between center levels after adjustment. In patients with burns > 20 % TBSA, Level 1 centers maintained lower mortality rates (adjusted OR=0.83, 95 % CI 0.79-0.88, p < 0.001).

CONCLUSION

Trauma center designation is associated with significant differences in burn outcomes. Level 1 centers, despite managing more severe cases, demonstrate lower mortality, emphasizing the importance of specialized care for burn patients. Standardizing burn care protocols and optimizing transfer practices may further improve outcomes for this high-acuity population.

摘要

背景

烧伤,尤其是那些涉及大面积总体表面积(TBSA)的烧伤,由于液体转移、代谢需求增加以及并发症易感性增加,带来了重大挑战。创伤中心的分级,从1级(最高 acuity)到3级,反映了资源、专业知识和护理方案的差异,这可能会影响患者的治疗结果。本研究评估了创伤中心分级对烧伤患者输血实践、并发症和死亡率的影响。

方法

查询创伤质量改进计划(TQIP)数据库(2017 - 2022年),通过ICD - 9/10编码识别烧伤患者。患者根据创伤中心分级进行分类:1级与非1级(2级和3级)。分析的结果包括输血实践(如浓缩红细胞、血浆、血小板)、住院并发症和死亡率。进行多变量逻辑回归分析,并对年龄、性别、TBSA百分比、吸入性损伤和损伤严重程度评分(ISS)进行调整。对TBSA > 20%的烧伤患者进行亚组分析。

结果

在72474例烧伤患者中,47%在1级中心接受治疗。1级中心的患者损伤严重程度更高,并发症发生率显著更高,包括呼吸衰竭、败血症和手术部位感染。尽管并发症发生率较高,但与非1级中心相比,1级中心的死亡率显著更低(调整后的OR = 0.46,95% CI 0.25 - 0.83,p = 0.011)。调整后,不同中心级别之间的输血实践没有显著差异。在TBSA > 20%的患者中,1级中心的死亡率维持在较低水平(调整后的OR = 0.83,95% CI 0.79 - 0.88,p < 0.001)。

结论

创伤中心分级与烧伤治疗结果的显著差异相关。1级中心尽管处理的病例更严重,但死亡率更低,强调了对烧伤患者进行专科护理的重要性。标准化烧伤护理方案和优化转运实践可能会进一步改善这一高 acuity 人群的治疗结果。

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