Zhang Shiming, Wu Min, Yin Jiayi, Du Meijun, Chen Jiali, Sakran Karim A, Yang Renjie, Song Jian, Zheng Qian, Shi Bing, Huang Hanyao
State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases and Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China.
State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases and Eastern Clinic, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China.
J Craniomaxillofac Surg. 2025 Sep;53(9):1495-1500. doi: 10.1016/j.jcms.2025.06.005. Epub 2025 Jun 30.
The aim of the study was to demonstrate the therapeutic outcomes after a family strategy for nasoalveolar molding (Family-NAM) in infants with unilateral complete cleft lip and palate.
Forty patients with unilateral complete cleft lip and palate were categorized into two groups: the group in which the Family-NAM was used and the control group without Family-NAM. The Family-NAM was applied seven days after birth until primary rhinoplasty, while the 3-D alveolar molding plates were applied until primary palatoplasty. Six parameters were measured to evaluate nasal symmetry, and palatal measurements were applied to evaluate the cleft palate size and morphology.
Before the primary surgical correction, the application of Family-NAM can significantly improve the preoperative nasal morphology. Patients with Family-NAM showed better nasal symmetry at 6-12-month post-operative follow-up compared with the control group. Compared to the control group, the Family-NAM group showed a significantly narrower cleft gap before primary cleft rhinoplasty and before primary palatoplasty.
The Family-NAM can effectively reduce the severity of preoperative clefts and improve the degree of asymmetry and postoperative nasal morphology. It is convenient for infant caregivers by avoiding frequent visits, minimizing complications, and simplifying the courses of preoperative molding treatment.
本研究的目的是证明采用家庭式鼻牙槽塑形策略(Family-NAM)治疗单侧完全性唇腭裂婴儿后的治疗效果。
40例单侧完全性唇腭裂患者被分为两组:采用Family-NAM的组和未采用Family-NAM的对照组。Family-NAM在出生后7天应用至初次鼻整形术,而三维牙槽塑形板应用至初次腭裂修复术。测量六个参数以评估鼻对称性,并应用腭部测量来评估腭裂大小和形态。
在初次手术矫正前,应用Family-NAM可显著改善术前鼻形态。与对照组相比,采用Family-NAM的患者在术后6至12个月的随访中鼻对称性更好。与对照组相比,Family-NAM组在初次腭裂鼻整形术和初次腭裂修复术前的腭裂间隙明显更窄。
Family-NAM可有效降低术前腭裂的严重程度,改善不对称程度和术后鼻形态。它避免了频繁就诊,减少了并发症,简化了术前塑形治疗过程,对婴儿护理者来说很方便。