Bockarie Tahir, Shanker Ankit, Jalloh Mohamed B, Kamara Alhaji M, Odland Maria Lisa, Wurie Haja, Ansumana Rashid, Lamin Joseph, Witham Miles, Oyebode Oyinlola, Davies Justine
Faculty of Life Sciences & Medicine, King's College London, London, UK
Warwick Medical School, University of Warwick, Coventry, UK.
BMJ Open. 2025 Jul 1;15(7):e095825. doi: 10.1136/bmjopen-2024-095825.
To examine the association between behavioural risk factors and their physiological sequelae among adults aged 40 and above in Bo District, Sierra Leone.
Cross-sectional study.
Household survey in Bo District, Sierra Leone.
The study included 1978 randomly sampled adults aged 40 and above (44.4% male and 55.6% female). The majority of participants were aged 40-49 years (34.5%). Data were collected using a household survey based on the validated WHO STEPs questionnaire.
Multivariable logistic regression analysis was performed to determine associations between behavioural risk factors (diet, physical activity and salt intake) and the presence of hypertension, diabetes and/or obesity, adjusting for sociodemographic variables.
The primary outcomes were the presence of hypertension, diabetes or overweight/obesity. Hypertension was defined as systolic blood pressure of ≥140 mm Hg and/or diastolic blood pressure of ≥90 (measured); diabetes as fasting glucose of ≥7.0 mmol/L, random plasma glucose level of ≥11.1 mmol/L or the use of antidiabetic medications (self-reported) and overweight/obesity as having a body mass index of ≥25 kg/m² (measured).
At least one physiological risk factor for cardiovascular diseases, that is, hypertension, obesity or diabetes, was present in 43.5% of participants. Hypertension was associated with urban living (OR=1.46, 95% CI (1.41 to 1.51)), older age (OR for 80+=3.98, 95% CI (3.70 to 4.28)), insufficient fruit and vegetable intake (OR=1.52, 95% CI (1.46 to 1.60)) and low physical activity (OR=1.35, 95% CI (1.27 to 1.43)). Diabetes was associated with urban residence (OR=1.84, 95% CI (1.66 to 2.05)), older age (OR for 70-79=3.82, 95% CI (3.28 to 4.45)), low fruit and vegetable consumption (OR=1.61, 95% CI (1.36 to 1.90)), high salt intake (OR=1.34, 95% CI (1.21 to 1.49)) and low physical activity (OR=1.47, 95% CI (1.26 to 1.71)). Obesity was associated with urban living (OR=1.66, 95% CI (1.59 to 1.72)), high salt intake from two or more sources (OR=1.21, 95% CI (1.17 to 1.25)) and low physical activity (OR=1.30, 95% CI (1.22 to 1.39)). Male sex (OR=0.37, 95% CI (0.36 to 0.38)) and older age (OR for 80+=0.39, 95% CI (0.35 to 0.43)) were protective factors.
In Bo District, nearly half of adults over 40 face hypertension, diabetes or obesity, especially urban dwellers, older age groups and those eating too few fruits and vegetables, consuming excess salt and getting little exercise. Public health efforts should focus on urban-targeted nutrition education, salt-reduction strategies, community exercise programmes and routine blood pressure and glucose screening, working with local leaders to ensure sustainable lifestyle changes and early disease detection.
研究塞拉利昂博城40岁及以上成年人行为风险因素与其生理后遗症之间的关联。
横断面研究。
塞拉利昂博城的家庭调查。
该研究纳入了1978名40岁及以上的随机抽样成年人(男性占44.4%,女性占55.6%)。大多数参与者年龄在40 - 49岁之间(占34.5%)。数据通过基于经过验证的世卫组织“STEPS”问卷的家庭调查收集。
进行多变量逻辑回归分析,以确定行为风险因素(饮食、身体活动和盐摄入量)与高血压、糖尿病和/或肥胖症之间的关联,并对社会人口统计学变量进行调整。
主要结局为高血压、糖尿病或超重/肥胖症的存在情况。高血压定义为收缩压≥140毫米汞柱和/或舒张压≥90(测量值);糖尿病定义为空腹血糖≥7.0毫摩尔/升、随机血糖水平≥11.1毫摩尔/升或使用抗糖尿病药物(自我报告),超重/肥胖症定义为体重指数≥25千克/平方米(测量值)。
43.5%的参与者至少存在一种心血管疾病的生理风险因素,即高血压、肥胖症或糖尿病。高血压与城市居住(比值比=1.46,95%置信区间(1.41至1.51))、年龄较大(80岁及以上的比值比=3.98,95%置信区间(3.70至4.28))、水果和蔬菜摄入量不足(比值比=1.52,95%置信区间(1.46至1.60))以及身体活动量低(比值比=1.35,95%置信区间(1.27至1.43))相关。糖尿病与城市居住(比值比=1.84,95%置信区间(1.66至2.05))、年龄较大(70 - 79岁的比值比=3.82,95%置信区间(3.28至4.45))、水果和蔬菜消费量低(比值比=1.61,95%置信区间(1.36至1.90))、高盐摄入量(比值比=1.34,95%置信区间(1.21至1.49))以及身体活动量低(比值比=1.47,95%置信区间(1.26至1.71))相关。肥胖症与城市居住(比值比=1.66,95%置信区间(1.59至1.72))、来自两种或更多来源的高盐摄入量(比值比=1.21,95%置信区间(1.17至1.25))以及身体活动量低(比值比=1.30,95%置信区间(1.22至1.39))相关。男性(比值比=0.37,95%置信区间(0.36至0.38))和年龄较大(80岁及以上的比值比=0.39,95%置信区间(0.35至0.43))是保护因素。
在博城,40岁以上的成年人中近一半面临高血压、糖尿病或肥胖症,尤其是城市居民、老年人群以及那些水果和蔬菜摄入过少、盐摄入过多且运动不足的人。公共卫生工作应侧重于针对城市的营养教育、减盐策略、社区锻炼计划以及常规血压和血糖筛查,与当地领导人合作以确保可持续的生活方式改变和疾病早期检测。