Wu Yuanrong, Li Qin, Shen Manxuan
School of Nursing and Health, Nanfang College·Guangzhou, Guangzhou, Guangdong Province, China.
Department of Gastrointestinal Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, China.
Sci Rep. 2025 Jul 1;15(1):21554. doi: 10.1038/s41598-025-07890-x.
In this study, we investigated the status quo of illness acceptance, community self-efficacy, and social isolation in elderly patients with Parkinson's disease (PD). We explored the effects of illness acceptance and community self-efficacy on the relationship between social isolation and loneliness in patients with PD based on the self-regulation theory model. We selected elderly patients with PD from the outpatient department of two Grade iii-A hospitals in Guangdong Province using convenience sampling. We collected data using a general information questionnaire. We used the Lubben Social Network Scale, UCLA Loneliness Scale, Community's Self-Efficacy Scale, and Acceptance of Illness Scale. Data were analyzed using descriptive statistics, Pearson's correlation coefficient, and bootstrap sampling to test the multiple mediation model. We recruited 142 elderly patients with PD. Their mean age was 69.30 years (standard deviation = 5.34, range from 60 to 89 years). Approximately 55.6% (n = 79) of the patients were male. The mean scores for community self-efficacy, social network, and illness acceptance were 11.03 ± 6.21, 13.29 ± 5.4, and 23.56 ± 6.871, respectively. Loneliness was negatively associated with illness acceptance (r = -0.536, p < 0.001) and community self-efficacy (r = -0.654, p < 0.001). The results of multiple mediation analysis indicated that illness acceptance (effect: -0.172, 95% confidence interval (CI) [-0.297, 0.067]) and community self-efficacy (effect: -0.271, 95% CI [-0.446, -0.115]) individually and collectively influenced the relationship between social isolation and loneliness (effect: -0.055, 95% CI [-0.105, -0.017]). The direct effect and mediating effect values accounted for 59.6% and 40.4% of the total effect value, respectively. Illness acceptance and community self-efficacy mediate the association between social isolation and loneliness. Interventions that help facilitate mutuality, illness acceptance, and community self-efficacy may help minimize loneliness in patients with PD.
在本研究中，我们调查了帕金森病（PD）老年患者的疾病接纳度、社区自我效能感和社会隔离状况。基于自我调节理论模型，我们探讨了疾病接纳度和社区自我效能感对PD患者社会隔离与孤独感之间关系的影响。我们采用便利抽样的方法，从广东省两家三级甲等医院的门诊部选取了PD老年患者。我们使用一般信息问卷收集数据。我们采用了鲁本社会网络量表、加州大学洛杉矶分校孤独感量表、社区自我效能感量表和疾病接纳量表。使用描述性统计、皮尔逊相关系数和自助抽样对数据进行分析，以检验多重中介模型。我们招募了142名PD老年患者。他们的平均年龄为69.30岁（标准差 = 5.34，年龄范围为60至89岁）。约55.6%（n = 79）的患者为男性。社区自我效能感、社会网络和疾病接纳度的平均得分分别为11.03±6.21、13.29±5.4和23.56±6.871。孤独感与疾病接纳度（r = -0.536，p < 0.001）和社区自我效能感（r = -0.654，p < 0.001）呈负相关。多重中介分析结果表明，疾病接纳度（效应：-0.172，95%置信区间（CI）[-0.297, 0.067]）和社区自我效能感（效应：-0.271，95% CI [-0.446, -0.115]）分别及共同影响社会隔离与孤独感之间的关系（效应：-0.055，95% CI [-0.105, -0.017]）。直接效应值和中介效应值分别占总效应值的59.6%和40.4%。疾病接纳度和社区自我效能感介导了社会隔离与孤独感之间的关联。有助于促进相互性、疾病接纳度和社区自我效能感的干预措施可能有助于减少PD患者的孤独感。
