A study of extracorporeal cardiac shock wave therapy combined with exercise rehabilitation in postoperative patients with PCI for CHD.

Coronary heart disease (CHD) affects a large number of patients, and their survival period with the condition is relatively long. Cardiac shock wave therapy (CSWT) is an anti-myocardial ischemic therapy. This study aims to investigate the rehabilitative effects and underlying mechanisms of CSWT combined with exercise rehabilitation in patients undergoing percutaneous coronary intervention (PCI) for CHD. The study was a prospective randomized controlled trial conducted at Yunnan Fuwai Cardiovascular Hospital from 2020 to 2022, enrolling 74 patients who underwent PCI for CHD. They were randomly assigned to two groups: a control group of 37 patients and a study group of 37 patients. The intervention consisted of CSWT combined with exercise rehabilitation. Following the intervention, patients in the study group demonstrated increases in peak oxygen uptake (peak VO2), high-density lipoprotein cholesterol (HDL-C) and other parameters compared to pre-treatment levels. The combination of CSWT and exercise rehabilitation was found to improve myocardial markers, related anti-inflammatory and anti-atherosclerotic indicators in patients with CHD. Moreover, it alleviated myocardial ischemia while enhancing parameters such as oxygen uptake in cardiopulmonary exercise testing (CPET). These findings may offer novel insights into anti-ischemic treatment and cardiac rehabilitation for patients with CHD in future clinical practice.