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中国中老年人群室外与室内空气污染物暴露与抑郁症之间的关联

Association between outdoor and indoor air pollutant exposure and depression among middle-aged and older adults in China.

作者信息

Zhao Zhixin, Chu Yanting, Chen Xingtong, Liu Tao

机构信息

Ansteel General Hospital, Anshan, China.

Baoding University of Technology, Baoding, China.

出版信息

Sci Rep. 2025 Jul 1;15(1):22162. doi: 10.1038/s41598-025-07185-1.

DOI:10.1038/s41598-025-07185-1
PMID:40594657
Abstract

Limited epidemiological studies have explored the association between outdoor and indoor air pollutants and depressive symptoms among middle-aged and elderly adults. We utilized data from the China Health and Retirement Longitudinal Study (CHARLS). Depressive symptoms were assessed using the 10-item Center for Epidemiologic Studies Depression Scale (CES-D 10), while indoor air pollution was self-reported. Outdoor air pollutant data were obtained from the China National Environmental Monitoring Center (CNEMC). Logistic regression was used to examine the association between exposure to outdoor air pollutants and indoor air pollutants from solid fuel use and depressive symptoms among middle-aged and older adults in China. The study found that each standard deviation (SD) increase in outdoor PM and SO was significantly associated with the occurrence of depressive symptoms. Exposure to indoor air pollution from solid fuel use for heating and cooking was also significantly linked to depressive symptoms. Indoor air pollution from solid fuel use for cooking may attenuate the association between outdoor PM and PM and depressive symptoms on a multiplicative scale. These findings highlight a significant correlation between depressive symptoms and exposure to both outdoor and indoor air pollutants in middle-aged and elderly adults.

摘要

有限的流行病学研究探讨了室外和室内空气污染物与中老年成年人抑郁症状之间的关联。我们使用了中国健康与养老追踪调查(CHARLS)的数据。抑郁症状采用10项流行病学研究中心抑郁量表(CES-D 10)进行评估,而室内空气污染则通过自我报告获取。室外空气污染物数据来自中国国家环境监测中心(CNEMC)。采用逻辑回归分析中国中老年成年人接触室外空气污染物以及固体燃料使用产生的室内空气污染物与抑郁症状之间的关联。研究发现,室外细颗粒物(PM)和二氧化硫(SO)每增加一个标准差(SD),与抑郁症状的发生显著相关。使用固体燃料进行取暖和烹饪导致的室内空气污染也与抑郁症状显著相关。使用固体燃料烹饪造成的室内空气污染可能会在乘法尺度上减弱室外细颗粒物(PM)和可吸入颗粒物(PM)与抑郁症状之间的关联。这些发现凸显了中老年成年人抑郁症状与接触室外和室内空气污染物之间的显著相关性。

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