Janarthanan Salai Dhavamathi, Ballae Ganeshrao Shonraj, Watt Kathleen, Hazarika Manali, Ve Ramesh S, H Vijaya Pai, Radhakrishnan Aiswaryah
Department of Optometry, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India.
School of Optometry and Vision Science, University of New South Wales, Sydney, Australia.
Sci Rep. 2025 Jul 1;15(1):21791. doi: 10.1038/s41598-025-06778-0.
Early-onset myopia (EOM) progresses more rapidly and sets a higher risk of developing high myopia, whereas late-onset myopia (LOM) is typically associated with lower refractive error. However, differences in visual function between these groups remain underexplored. This cross-sectional study compared high-contrast visual acuity, low-contrast visual acuity, contrast sensitivity function (CSF), blur perception, and depth of focus in individuals with EOM and LOM. Twenty participants (10 EOM, 10 LOM) aged 18-35 years with myopia ranging from - 0.50 to - 6.00 D were included. Visual function assessments were conducted using MATLAB and PsychoPy software, with all measurements taken under full-distance spectacle correction. While high-contrast and low-contrast visual acuity showed no significant differences, CSF parameters showed significant differences. The area under the curve, peak spatial frequency, and cutoff spatial frequency were significantly lower in EOM than in LOM (p = 0.019, 0.032, and 0.005, respectively). Blur perception thresholds also varied, though statistical significance was not reached. These findings suggest that individuals with EOM may show compromised contrast sensitivity, possibly affecting their overall visual quality. Understanding these functional differences can help in developing targeted interventions for myopia management, ensuring personalized approaches to optimize visual performance across different onset groups.
早发性近视(EOM)进展更快,发生高度近视的风险更高,而迟发性近视(LOM)通常与较低的屈光不正相关。然而,这些群体之间视觉功能的差异仍未得到充分研究。这项横断面研究比较了早发性近视和迟发性近视个体的高对比度视力、低对比度视力、对比敏感度函数(CSF)、模糊感知和焦深。纳入了20名年龄在18 - 35岁、近视度数在-0.50至-6.00 D之间的参与者(10名早发性近视,10名迟发性近视)。使用MATLAB和PsychoPy软件进行视觉功能评估,所有测量均在全距离眼镜矫正下进行。虽然高对比度和低对比度视力没有显著差异,但CSF参数存在显著差异。早发性近视的曲线下面积、峰值空间频率和截止空间频率显著低于迟发性近视(分别为p = 0.019、0.032和0.005)。模糊感知阈值也有所不同,尽管未达到统计学显著性。这些发现表明,早发性近视个体可能表现出对比敏感度受损,这可能会影响他们的整体视觉质量。了解这些功能差异有助于制定针对性的近视管理干预措施,确保针对不同发病群体采取个性化方法来优化视觉表现。