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本文引用的文献

1
Sex Differences in Anxiety and Depression Conditions among Cancer Patients: A Systematic Review and Meta-Analysis.癌症患者焦虑和抑郁状况的性别差异：一项系统评价与荟萃分析。
Cancers (Basel). 2024 May 22;16(11):1969. doi: 10.3390/cancers16111969.
2
Non-pharmacological interventions for chemotherapy-induced diarrhoea and constipation management: A scoping review.非药物干预措施在化疗引起的腹泻和便秘管理中的应用：范围综述。
Eur J Oncol Nurs. 2024 Feb;68:102485. doi: 10.1016/j.ejon.2023.102485. Epub 2023 Dec 9.
3
Cancer, now what? A cross-sectional study examining physical symptoms, subjective well-being, and psychological flexibility.癌症，现在怎么办？一项关于身体症状、主观幸福感和心理灵活性的横断面研究。
Health Psychol Behav Med. 2023 Oct 13;11(1):2266220. doi: 10.1080/21642850.2023.2266220. eCollection 2023.
4
Acceptance and commitment therapy processes and their association with distress in cancer: a systematic review and meta-analysis.接纳与承诺疗法的过程及其与癌症患者痛苦的关联：系统综述和荟萃分析。
Health Psychol Rev. 2024 Sep;18(3):456-477. doi: 10.1080/17437199.2023.2261518. Epub 2023 Oct 4.
5
Effectiveness of acceptance and commitment therapy on psychological flexibility, fatigue, sleep disturbance, and quality of life of patients with cancer: A meta-analysis of randomized controlled trials.接受与承诺疗法对癌症患者心理灵活性、疲劳、睡眠障碍和生活质量的影响：一项随机对照试验的荟萃分析。
Worldviews Evid Based Nurs. 2023 Dec;20(6):582-592. doi: 10.1111/wvn.12652. Epub 2023 May 16.
6
The Impact of Depression and Anxiety on Adult Cancer Patients' Health-Related Quality of Life.抑郁和焦虑对成年癌症患者健康相关生活质量的影响。
J Clin Med. 2023 Mar 12;12(6):2196. doi: 10.3390/jcm12062196.
7
Quality of life, distress, anxiety and depression of ambulatory cancer patients receiving chemotherapy.接受化疗的门诊癌症患者的生活质量、痛苦、焦虑和抑郁
Med Pharm Rep. 2022 Oct;95(4):418-429. doi: 10.15386/mpr-2458. Epub 2022 Oct 27.
8
Proportion and related factors of depression and anxiety for inpatients with lung cancer in China: a hospital-based cross-sectional study.中国肺癌住院患者抑郁和焦虑的比例及其相关因素：一项基于医院的横断面研究。
Support Care Cancer. 2022 Jun;30(6):5539-5549. doi: 10.1007/s00520-022-06961-3. Epub 2022 Mar 23.
9
Psychometric properties of the Spanish version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30).欧洲癌症研究与治疗组织生活质量问卷（EORTC QLQ-C30）西班牙版的心理测量特性。
Qual Life Res. 2022 Jun;31(6):1859-1869. doi: 10.1007/s11136-021-03068-w. Epub 2021 Dec 20.
10
Effectiveness of acceptance and commitment therapy for mental illness in cancer patients: A systematic review and meta-analysis of randomised controlled trials.接受与承诺疗法对癌症患者精神疾病的疗效：随机对照试验的系统评价和荟萃分析。
Int J Clin Pract. 2021 Jun;75(6):e13982. doi: 10.1111/ijcp.13982. Epub 2021 Jan 23.

焦虑、抑郁、生活质量与心理灵活性的中介作用：一项针对西班牙癌症患者的研究。

Anxiety, depression, quality of life and the mediating role of psychological flexibility: A study on Spanish cancer patients.

作者信息

García-Torres Francisco, García-Carmona Margarita, Gómez-Solís Ángel, Jurado-González Francisco, Jablonski Marcin, Jaén-Moreno María José, Aranda Enrique

机构信息

Department of Psychology, Faculty of Educational Sciences and Psychology, University of Cordoba, San Alberto Magno Av, 14071, Cordoba, Spain.

Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Cordoba, Spain.

出版信息

Sci Rep. 2025 Jul 2;15(1):22530. doi: 10.1038/s41598-025-06942-6.

DOI:10.1038/s41598-025-06942-6
PMID:40595087
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12215487/
Abstract

Anxiety, depression and psychological flexibility appear to be correlated with quality of life in cancer patients. However, the mediating role of psychological flexibility between emotional distress and quality of life are unclear. The aim of the study was to investigate the mediating role of psychological flexibility in the relationships between anxiety, depression, and quality of life in cancer patients undergoing treatment. A hundred and nineteen cancer patients participated in the study by completing the Hospital Anxiety and Depression Scale, the Action and Acceptance Questionnaire II, and the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire, version 3. Anxiety and depression correlated with psychological flexibility and quality of life. Psychological flexibility correlated with the quality of life scales but not with the diarrhoea and constipation. Mediation analysis showed that depression and anxiety indirectly influenced cognitive and social function through psychological flexibility. Depression indirectly influenced emotional functioning, dyspnoea and insomnia. The results obtained suggest that psychological flexibility may affect the relationship between emotional distress and different aspects of quality of life for cancer patients.Trial registration This research has been registered in www.ClinicalTrials.gov , identifier [NCT05126823] in 19/11/2021.

摘要

焦虑、抑郁和心理灵活性似乎与癌症患者的生活质量相关。然而，心理灵活性在情绪困扰和生活质量之间的中介作用尚不清楚。本研究的目的是调查心理灵活性在接受治疗的癌症患者的焦虑、抑郁和生活质量之间关系中的中介作用。119名癌症患者通过完成医院焦虑抑郁量表、行动与接受问卷II以及欧洲癌症研究与治疗组织生活质量问卷第3版参与了本研究。焦虑和抑郁与心理灵活性及生活质量相关。心理灵活性与生活质量量表相关，但与腹泻和便秘无关。中介分析表明，抑郁和焦虑通过心理灵活性间接影响认知和社会功能。抑郁间接影响情绪功能、呼吸困难和失眠。所得结果表明，心理灵活性可能会影响癌症患者情绪困扰与生活质量不同方面之间的关系。试验注册 本研究已于2021年11月19日在www.ClinicalTrials.gov上注册，标识符为[NCT05126823]。