Richter G M, Kauffmann G W, Wimmer B
Radiologe. 1985 Aug;25(8):364-70.
Experimental results of embolization of normal organs did not clarify the value of transcatheter vessel occlusion in the treatment of renal carcinoma. In experimental embolization of chemically induced renal rat tumors the concept of capillary embolization was developed and showed excellent results even in end-stage tumors. In consequence this concept was adapted and transferred to clinical tumor embolization. Of 30 patients, that have been embolized up to now using Ethibloc in combination with 40% glucose as occlusion medium, one case is reported herein with a very favourable outcome. The female patient had intensive venous infiltration of a renal carcinoma accompanied by severe hematuria (T3NxM0V2). Because a patient that seems to be practically cured 30 months after embolization demonstrating massive tumor shrinkage to less than 10% of the original size in CT-controls the use of transcatheter vessel occlusion should again be investigated in association with surgical alternatives.
正常器官栓塞的实验结果并未阐明经导管血管闭塞术在治疗肾癌中的价值。在化学诱导的大鼠肾肿瘤实验性栓塞中,发展出了毛细血管栓塞的概念,即使在晚期肿瘤中也显示出了优异的效果。因此,这一概念被应用并转移到临床肿瘤栓塞中。到目前为止,已有30例患者使用Ethibloc联合40%葡萄糖作为闭塞介质进行了栓塞,本文报告其中1例效果非常良好的病例。该女性患者患有肾癌伴严重静脉浸润及严重血尿(T3NxM0V2)。由于该患者在栓塞后30个月似乎已实际治愈,CT检查显示肿瘤大幅缩小至原始大小的不到10%,因此应再次研究经导管血管闭塞术与手术替代方案联合使用的情况。