Wang Han, Zhang Wen, Zhang Ru, Song Ying, Tang Shunding, Zhang Caiyan, Zhao Yajing, Zhang Xiaoqing
School of Public Health, Kunming Medical University, Kunming, China.
Fu Wai Yunnan Cardiovascular Hospital, Kunming, China.
Sci Rep. 2025 Jul 1;15(1):22035. doi: 10.1038/s41598-025-04504-4.
Patient-reported outcomes (PROs) are assessments based on patients' self-perception. This study aimed to explore whether WeChat-based health education is more effective than traditional health education in terms of improving PROs for hypertensive patients during a 3-month period. This prospective, single-center, single-blind randomized controlled trial was conducted from April to August 2022 at the hypertension ward of Yunnan Province Fuwai Cardiovascular Hospital. A total of 96 patients who were aged 18-75 years and diagnosed with primary hypertension for the first time were recruited. The participants were randomly assigned to either the WeChat health education group or the conventional care group at a 1:1 ratio. The intervention lasted for 3 months, with PRO scales administered at baseline (T0), 1 month postintervention (T1), and 3 months postintervention (T2). The experiment ultimately enrolled 96 people, with a mean age of 41 years for the intervention group and 43 years for the control group. Regarding the main outcomes, the total PRO scores of the WeChat group significantly increased from 79.29 points at baseline to 83.68 points after the interventions (95% CI - 7.373, - 1.400; P < 0.05). Additionally, there were significant intergroup differences at 1 month postintervention (TOT: mean difference in change between groups: 3.95, 95% CI 0.127, 7.766, P < 0.05) and at 3 months postintervention (TOT: mean difference in change between groups: 5.05, 95% CI 1.26, 8.833, P < 0.05). This trial demonstrated that WeChat-based telehealth interventions have a positive effect on PROs. The incorporation of digital health education and telehealth interventions can serve as an adjuvant treatment for hypertensive patients.
患者报告结局(PROs)是基于患者自我认知的评估。本研究旨在探讨在3个月期间,基于微信的健康教育在改善高血压患者的PROs方面是否比传统健康教育更有效。这项前瞻性、单中心、单盲随机对照试验于2022年4月至8月在云南省阜外心血管病医院高血压病房进行。共招募了96名年龄在18 - 75岁且首次诊断为原发性高血压的患者。参与者以1:1的比例随机分配到微信健康教育组或传统护理组。干预持续3个月,在基线(T0)、干预后1个月(T1)和干预后3个月(T2)进行PRO量表评估。该实验最终纳入96人,干预组的平均年龄为41岁,对照组为43岁。关于主要结局,微信组的PRO总分从基线时的79.29分显著提高到干预后的83.68分(95%CI -7.373,-1.400;P<0.05)。此外,在干预后1个月(TOT:组间变化的平均差异:3.95,95%CI 0.127,7.766,P<0.05)和干预后3个月(TOT:组间变化的平均差异:5.05,95%CI 1.26,8.833,P<0.05)存在显著的组间差异。该试验表明,基于微信的远程医疗干预对PROs有积极影响。将数字健康教育和远程医疗干预纳入可以作为高血压患者的辅助治疗方法。