Noguera Sharlene I, Nicanor Katherine S Aniana, Ang Robert Edward T, Cruz Emerson M
Asian Eye Institute, 9th Floor PHINMA Plaza, Rockwell Center, Makati City, 1200, Philippines.
BMC Ophthalmol. 2025 Jul 1;25(1):380. doi: 10.1186/s12886-025-04196-4.
This study described the clinical profile and post-operative outcomes of patients who underwent pterygium surgery at an ambulatory eye center in the Philippines over a ten-year period.
This retrospective study analyzed medical records of 462 eyes from 408 patients who underwent pterygium surgery by a single surgeon between February 2013 and August 2023. The study examined the clinical characteristics of patients with pterygium and evaluated the recurrence rates of three treatment methods: pterygium excision with conjunctival autograft (CAG), pterygium excision with dehydrated amniotic membrane graft (DAG), and primary excision with mitomycin C application. Descriptive statistics were used for analysis of patient demographics, clinical profile, and postoperative outcomes.
The mean patient age was 48 years (range 17-81), with a slight male predominance (57%). Nasal pterygium was the most common type (72%), followed by bipolar (8%) and temporal (3%) pterygium. Most cases were primary (81%), with T2G1 being the most common grading. Conjunctival autograft was the predominant surgical technique (94%), followed by dehydrated amniotic membrane graft (5%) and primary excision with mitomycin C application (1%). The overall recurrence rate was 1%, with conjunctival autograft showing the lowest rate, compared to dehydrated amniotic membrane graft and primary excision with mitomycin C. The complication rate was 4.5%, primarily minor findings such as conjunctival granuloma, wound dehiscence, and residual pterygium.
Most pterygium cases presented as primary and in the nasal area with T2G1 grading. This study supports conjunctival autograft as the preferred surgical technique for pterygium because of the low recurrence and complication rates.
本研究描述了在菲律宾一家门诊眼科中心接受翼状胬肉手术的患者在十年期间的临床特征和术后结果。
这项回顾性研究分析了2013年2月至2023年8月间由一名外科医生为408例患者实施的462只眼翼状胬肉手术的病历。该研究检查了翼状胬肉患者的临床特征,并评估了三种治疗方法的复发率:结膜自体移植翼状胬肉切除术(CAG)、脱水羊膜移植翼状胬肉切除术(DAG)以及丝裂霉素C应用的原发性切除术。描述性统计用于分析患者人口统计学、临床特征和术后结果。
患者平均年龄为48岁(范围17 - 81岁),男性略占优势(57%)。鼻侧翼状胬肉是最常见的类型(72%),其次是双侧(8%)和颞侧(3%)翼状胬肉。大多数病例为原发性(81%),T2G1是最常见的分级。结膜自体移植是主要的手术技术(94%),其次是脱水羊膜移植(5%)和丝裂霉素C应用的原发性切除术(1%)。总体复发率为1%,与脱水羊膜移植和丝裂霉素C应用的原发性切除术相比,结膜自体移植的复发率最低。并发症发生率为4.5%,主要是结膜肉芽肿、伤口裂开和残留翼状胬肉等轻微情况。
大多数翼状胬肉病例表现为原发性,位于鼻侧,分级为T2G1。由于复发率和并发症率低,本研究支持结膜自体移植作为翼状胬肉的首选手术技术。