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VExUS评分对因充血性心力衰竭在急诊科接受随访患者死亡率的预测效能:一项前瞻性横断面研究。

Effectiveness of VExUS scores for predicting mortality among patients followed up in the emergency department due to congestive heart failure: a prospective cross-sectional study.

作者信息

Senay Fatih Burak, Kaya Murtaza, Atlanoglu Sahinde, Ulu Mehmed

机构信息

Medical Faculty, Department of Emergency Medicine, Kutahya Healthy Sciences University, Kuyahya City Hospital, Kutahya, Turkey.

Medical Faculty, Department of Radiology, Kutahya Healthy Sciences University, Kuyahya City Hospital, Kutahya, Turkey.

出版信息

BMC Emerg Med. 2025 Jul 1;25(1):101. doi: 10.1186/s12873-025-01271-3.

DOI:10.1186/s12873-025-01271-3
PMID:40597631
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12211217/
Abstract

BACKGROUND/AIM: Congestive Heart Failure (CHF) is a major contributor to emergency department (ED) visits and mortality. Traditional diagnostic tools may not fully capture systemic venous congestion, which is a critical factor in CHF prognosis. The Venous Excess Ultrasound Score (VExUS) is a novel ultrasonographic tool that systematically evaluates venous congestion. This study aimed to assess the effectiveness of VExUS scores in predicting 30-day mortality in patients presenting to the ED with CHF symptoms.

METHODS

This was a prospective, cross-sectional study involving 47 adult patients presenting to the ED with clinical signs of CHF. Patients were assigned VExUS scores of 1, 2, or 3 based on ultrasonographic findings. Laboratory values, PV Doppler flow patterns, and diameters were recorded. Logistic regression and ROC curve analyses were conducted to evaluate the predictive value of VExUS scores and PV diameter on 30-day mortality.

RESULTS

Higher VExUS scores were associated with increased mortality. Specifically, patients with a VExUS score of 3 had significantly higher 30-day mortality compared to those with a score of 1 (OR = 15.92,  = 0.037). A PV diameter ≥ 10 mm predicted mortality with 92.31% sensitivity. Significant correlations were also found between VExUS scores and PV Doppler findings, PV diameter, and other ultrasonographic parameters.

CONCLUSION

Higher VExUS scores appear to be associated with increased 30-day mortality in CHF patients presenting to the emergency department, supporting its potential utility as a noninvasive prognostic tool. Its integration into routine ED assessment may help support risk stratification and guide more targeted management strategies.

CLINICAL TRIAL NUMBER

Not applicable.

摘要

背景/目的:充血性心力衰竭(CHF)是急诊科就诊和死亡的主要原因。传统的诊断工具可能无法完全捕捉全身静脉淤血情况,而这是CHF预后的关键因素。静脉过度超声评分(VExUS)是一种系统评估静脉淤血的新型超声检查工具。本研究旨在评估VExUS评分对因CHF症状就诊于急诊科患者30天死亡率的预测效果。

方法

这是一项前瞻性横断面研究,纳入了47例因CHF临床症状就诊于急诊科的成年患者。根据超声检查结果为患者分配VExUS评分为1、2或3。记录实验室值、门静脉多普勒血流模式和直径。进行逻辑回归和ROC曲线分析,以评估VExUS评分和门静脉直径对30天死亡率的预测价值。

结果

较高的VExUS评分与死亡率增加相关。具体而言,VExUS评分为3的患者30天死亡率显著高于评分为1的患者(OR = 15.92,P = 0.037)。门静脉直径≥10 mm预测死亡率的敏感度为92.31%。还发现VExUS评分与门静脉多普勒检查结果、门静脉直径和其他超声参数之间存在显著相关性。

结论

较高的VExUS评分似乎与因CHF就诊于急诊科患者的30天死亡率增加相关,支持其作为一种无创预后工具的潜在效用。将其纳入急诊科常规评估可能有助于支持风险分层并指导更具针对性的管理策略。

临床试验编号

不适用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b488/12211217/2e40067d80fd/12873_2025_1271_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b488/12211217/b4cbd391fcb5/12873_2025_1271_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b488/12211217/2e40067d80fd/12873_2025_1271_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b488/12211217/b4cbd391fcb5/12873_2025_1271_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b488/12211217/2e40067d80fd/12873_2025_1271_Fig2_HTML.jpg

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Oman Med J. 2024 May 30;39(3):e625. doi: 10.5001/omj.2024.65. eCollection 2024 May.
3
Assessment of venous congestion with venous excess ultrasound score in the prognosis of acute heart failure in the emergency department: a prospective study.
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Eur Heart J Open. 2024 Jul 10;4(5):oeae050. doi: 10.1093/ehjopen/oeae050. eCollection 2024 Sep.
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The VExUS score and mortality in patients with Acute Kidney Injury: findings from a multidisciplinary prospective study.急性肾损伤患者的VExUS评分与死亡率:一项多学科前瞻性研究的结果
Med Ultrason. 2024 Dec 19;26(4):356-361. doi: 10.11152/mu-4418. Epub 2024 Aug 7.
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