Sultana Razia, Mirdha Ranu Rekha, Shakya Megha, Mahadik Kalpana
Department of Obstetrics & Gynecology, R.D. Gardi Medical College, Surasa, Ujjain, 456006, India.
BMC Infect Dis. 2025 Jul 1;25(1):832. doi: 10.1186/s12879-025-11217-6.
Surgical site infection continues to be a significant source of morbidity and mortality especially in developing countries. Data pertaining to incidence and risk factors following obstetric surgeries are scarce. This study aims to identify risk factors and microbiological etiology of SSI in patients undergoing cesarean section in a teaching tertiary care hospital in Central India.
450 in-patient women who underwent cesarean for various indications were enrolled for the study and followed up for 30 days. Patients who reported between July 2022 to June 2023 were included in study and analyzed as per CDC definition and methodology. Incidence, risk factors like rural location, patients who are referred, duration of rupture of membrane, timing of prophylactic antibiotic, duration of surgery and microbiological etiology for SSI were noted from data collected.
The incidence of SSI is 13.7%. Rural location (OR 2.08), low socioeconomic status (OR 3.1), multiparity (OR 3.0), obesity (OR 4.05), emergency status (OR 4.63), increased duration of rupture of membrane (OR 8.3), prolonged labor (OR 11.7) and increased preoperative stay (OR 4.24) due to associated morbidities are the risk factors for SSI identified by univariate logistic regression model. Increase in each hour duration of surgery and inappropriate timing of antibiotic prophylaxis increased the risk of SSI by nearly double.
Rate of SSI in cesarean is 13.7%. Low socioeconomic status, rural locations, emergency status of surgery, long intra-operative period and time of prophylactic antibiotic are major risk factors for SSI in cesarean delivery.
Not Applicable.
手术部位感染仍然是发病和死亡的重要原因,尤其是在发展中国家。关于产科手术后感染发生率和危险因素的数据很少。本研究旨在确定印度中部一家教学型三级护理医院剖宫产患者手术部位感染的危险因素和微生物病因。
450例因各种指征行剖宫产的住院妇女纳入本研究,并随访30天。纳入2022年7月至2023年6月期间报告的患者,并根据美国疾病控制与预防中心(CDC)的定义和方法进行分析。从收集的数据中记录手术部位感染的发生率、危险因素,如农村地区、转诊患者、胎膜破裂时间、预防性抗生素使用时间、手术时间以及手术部位感染的微生物病因。
手术部位感染的发生率为13.7%。单因素逻辑回归模型确定的手术部位感染危险因素包括农村地区(比值比[OR] 2.08)、社会经济地位低(OR 3.1)、多胎妊娠(OR 3.0)、肥胖(OR 4.05)、急诊状态(OR 4.63)、胎膜破裂时间延长(OR 8.3)、产程延长(OR 11.7)以及因相关疾病导致术前住院时间延长(OR 4.24)。手术时间每增加一小时以及预防性抗生素使用时机不当会使手术部位感染风险增加近一倍。
剖宫产手术部位感染率为13.7%。社会经济地位低、农村地区、手术急诊状态、手术时间长以及预防性抗生素使用时间是剖宫产手术部位感染的主要危险因素。
不适用。