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人口统计学特征、非计划状态及术中情况会增加剖宫产手术部位感染:印度中部一项前瞻性研究的结论

Demographic profile, unplanned status and intraoperative situations increase surgical site infection in cesarean delivery: conclusions from a prospective study in central India.

作者信息

Sultana Razia, Mirdha Ranu Rekha, Shakya Megha, Mahadik Kalpana

机构信息

Department of Obstetrics & Gynecology, R.D. Gardi Medical College, Surasa, Ujjain, 456006, India.

出版信息

BMC Infect Dis. 2025 Jul 1;25(1):832. doi: 10.1186/s12879-025-11217-6.

DOI:10.1186/s12879-025-11217-6
PMID:40597718
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12211485/
Abstract

BACKGROUND

Surgical site infection continues to be a significant source of morbidity and mortality especially in developing countries. Data pertaining to incidence and risk factors following obstetric surgeries are scarce. This study aims to identify risk factors and microbiological etiology of SSI in patients undergoing cesarean section in a teaching tertiary care hospital in Central India.

METHODS

450 in-patient women who underwent cesarean for various indications were enrolled for the study and followed up for 30 days. Patients who reported between July 2022 to June 2023 were included in study and analyzed as per CDC definition and methodology. Incidence, risk factors like rural location, patients who are referred, duration of rupture of membrane, timing of prophylactic antibiotic, duration of surgery and microbiological etiology for SSI were noted from data collected.

RESULTS

The incidence of SSI is 13.7%. Rural location (OR 2.08), low socioeconomic status (OR 3.1), multiparity (OR 3.0), obesity (OR 4.05), emergency status (OR 4.63), increased duration of rupture of membrane (OR 8.3), prolonged labor (OR 11.7) and increased preoperative stay (OR 4.24) due to associated morbidities are the risk factors for SSI identified by univariate logistic regression model. Increase in each hour duration of surgery and inappropriate timing of antibiotic prophylaxis increased the risk of SSI by nearly double.

CONCLUSION

Rate of SSI in cesarean is 13.7%. Low socioeconomic status, rural locations, emergency status of surgery, long intra-operative period and time of prophylactic antibiotic are major risk factors for SSI in cesarean delivery.

CLINICAL TRIAL

Not Applicable.

摘要

背景

手术部位感染仍然是发病和死亡的重要原因,尤其是在发展中国家。关于产科手术后感染发生率和危险因素的数据很少。本研究旨在确定印度中部一家教学型三级护理医院剖宫产患者手术部位感染的危险因素和微生物病因。

方法

450例因各种指征行剖宫产的住院妇女纳入本研究,并随访30天。纳入2022年7月至2023年6月期间报告的患者,并根据美国疾病控制与预防中心(CDC)的定义和方法进行分析。从收集的数据中记录手术部位感染的发生率、危险因素,如农村地区、转诊患者、胎膜破裂时间、预防性抗生素使用时间、手术时间以及手术部位感染的微生物病因。

结果

手术部位感染的发生率为13.7%。单因素逻辑回归模型确定的手术部位感染危险因素包括农村地区(比值比[OR] 2.08)、社会经济地位低(OR 3.1)、多胎妊娠(OR 3.0)、肥胖(OR 4.05)、急诊状态(OR 4.63)、胎膜破裂时间延长(OR 8.3)、产程延长(OR 11.7)以及因相关疾病导致术前住院时间延长(OR 4.24)。手术时间每增加一小时以及预防性抗生素使用时机不当会使手术部位感染风险增加近一倍。

结论

剖宫产手术部位感染率为13.7%。社会经济地位低、农村地区、手术急诊状态、手术时间长以及预防性抗生素使用时间是剖宫产手术部位感染的主要危险因素。

临床试验

不适用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c010/12211485/cd9bd4486c4f/12879_2025_11217_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c010/12211485/cd9bd4486c4f/12879_2025_11217_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c010/12211485/cd9bd4486c4f/12879_2025_11217_Fig1_HTML.jpg

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本文引用的文献

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Front Surg. 2024 Aug 20;11:1379410. doi: 10.3389/fsurg.2024.1379410. eCollection 2024.
2
The incidence of surgical site infection and its predictors among women delivered via cesarean sections in Ethiopia: a systematic review and meta-analysis.埃塞俄比亚剖宫产分娩女性手术部位感染的发生率及其预测因素:一项系统评价和荟萃分析
Front Med (Lausanne). 2024 Apr 25;11:1395158. doi: 10.3389/fmed.2024.1395158. eCollection 2024.
3
Incidence, Bacterial Profile and Predictors of Surgical Site Infection After Cesarean Section in Ethiopia, A Prospective Cohort Study.
埃塞俄比亚剖宫产术后手术部位感染的发病率、细菌谱及预测因素:一项前瞻性队列研究
Int J Womens Health. 2023 Oct 13;15:1547-1560. doi: 10.2147/IJWH.S425632. eCollection 2023.
4
Healthcare Cost and Outcomes Associated With Surgical Site Infection and Patient Outcomes in Low- and Middle-Income Countries.低收入和中等收入国家手术部位感染相关的医疗成本、结局及患者预后
Cureus. 2023 Jul 26;15(7):e42493. doi: 10.7759/cureus.42493. eCollection 2023 Jul.
5
Global incidence of surgical site infections following caesarean section: a systematic review and meta-analysis.全球剖宫产术后手术部位感染发生率:系统评价和荟萃分析。
J Hosp Infect. 2023 Sep;139:82-92. doi: 10.1016/j.jhin.2023.05.019. Epub 2023 Jun 10.
6
Evaluation of independent risk factors associated with surgical site infections from caesarean section.评估剖宫产术切口感染的独立危险因素。
Arch Gynecol Obstet. 2023 Dec;308(6):1775-1783. doi: 10.1007/s00404-022-06885-7. Epub 2022 Dec 26.
7
Postoperative sepsis after colorectal surgery: a prospective single-center observational study and review of the literature.结直肠手术后的术后脓毒症:一项前瞻性单中心观察性研究及文献综述
Prz Gastroenterol. 2022;17(1):47-51. doi: 10.5114/pg.2021.106083. Epub 2021 May 23.
8
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Infect Prev Pract. 2020 Sep 9;2(4):100090. doi: 10.1016/j.infpip.2020.100090. eCollection 2020 Dec.
9
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Acta Obstet Gynecol Scand. 2021 Dec;100(12):2167-2175. doi: 10.1111/aogs.14235. Epub 2021 Aug 6.
10
Post cesarean section surgical site infection and associated factors among women who delivered in public hospitals in Harar city, Eastern Ethiopia: A hospital-based analytic cross-sectional study.在埃塞俄比亚东部哈拉尔市公立医院分娩的女性中,剖宫产术后手术部位感染及其相关因素:一项基于医院的分析性横断面研究。
PLoS One. 2021 Jun 23;16(6):e0253194. doi: 10.1371/journal.pone.0253194. eCollection 2021.