Li Yuman, Cui Ying, Mo Zhixin, Huang Xiaofeng, Chi Mingsi, Guo Tai, Huang Zhongning
Department of ophthalmology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, 106 Zhongshan Er Road, Guangzhou, 510080, Guangdong Province, China.
School of Medicine, South China University of Technology, Guangzhou, 510641, Guangdong Province, China.
BMC Ophthalmol. 2025 Jul 1;25(1):377. doi: 10.1186/s12886-025-04174-w.
To describe a case of non-arteritic posterior ischemic optic neuropathy (NA-PION).
One 54-year-old male with a history of hypertension and poor blood pressure control suffered from sudden decreases in color vision and vision over five days. On funduscopy, he had mild nasal elevation of the optic disc in the right eye with blurred margins. Retinal examination and fluorescein angiography demonstrated delayed filling of the inferior nasal retinal artery. A magnetic resonance imaging (MRI) scan of the orbit revealed swelling and tortuosity of the right optic nerve, but no evidence of acute ophthalmic artery obstruction. On the basis of the above findings, he was diagnosed with probable non-arteritic posterior ischemic optic neuropathy.
NA-PION, an exclusion diagnosis, is a rare ischemic optic neuropathy that typically presents with acute, painless visual loss in one or both eyes. During this clinical scenario, we review considerations for differential diagnosis and useful diagnostic tests for NA-PION.
描述一例非动脉炎性后部缺血性视神经病变(NA-PION)病例。
一名54岁男性,有高血压病史且血压控制不佳,在五天内出现色觉和视力突然下降。眼底检查发现,他右眼视盘轻度向鼻侧隆起,边缘模糊。视网膜检查和荧光素血管造影显示鼻下视网膜动脉充盈延迟。眼眶磁共振成像(MRI)扫描显示右侧视神经肿胀、迂曲,但未发现急性眼动脉阻塞的迹象。根据上述发现,他被诊断为可能的非动脉炎性后部缺血性视神经病变。
NA-PION是一种排除性诊断,是一种罕见的缺血性视神经病变,通常表现为单眼或双眼急性无痛性视力丧失。在此临床病例中,我们回顾了NA-PION的鉴别诊断要点和有用的诊断检查。