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一名克罗恩病患者的小肠狭窄:一种无关病因

Small Bowel Stricture in a Crohn's Patient: An Unrelated Etiology.

作者信息

Peddu Dhiraj K, Kubina Matthew, Mishra Ankit, Stone Molly, Zou Winnie, Shi Jiaqi, Kestenbaum David C, Regenbogen Scott E, Berinstein Jeffrey A

机构信息

Department of Gastroenterology and Hepatology, Michigan Medicine, Ann Arbor, Michigan, USA.

Department of Pathology and Clinical Labs, University of Michigan, Ann Arbor, Michigan, USA.

出版信息

Case Rep Gastrointest Med. 2025 Jun 24;2025:6697889. doi: 10.1155/crgm/6697889. eCollection 2025.

Abstract

Small bowel strictures are a common complication of Crohn's disease (CD), which can lead to obstruction, perforation, and fistula formation. However, strictures can stem from other etiologies in CD patients, including malignancy, prior surgery, radiation, and ischemia. We present a patient who developed a new long-segment jejunal and ileal stricture within 2 months after ileocolic resection. What was initially treated as worsening CD was ultimately an unrelated ischemic stricture due to suspected superior mesenteric artery thrombosis following ileocolic resection. The contrasting location of the stricture compared to her previous disease, timing of progression, and lack of response to anti-inflammatory treatment prompted a reassessment of the underlying disease process.

摘要

小肠狭窄是克罗恩病(CD)的常见并发症,可导致肠梗阻、穿孔和瘘管形成。然而,CD患者的狭窄也可能源于其他病因,包括恶性肿瘤、既往手术、放疗和缺血。我们报告一名患者,在回结肠切除术后2个月内出现了新的长段空肠和回肠狭窄。最初被当作病情恶化的CD来治疗,最终发现是由于回结肠切除术后疑似肠系膜上动脉血栓形成导致的无关的缺血性狭窄。与她之前疾病相比,狭窄的位置、进展时间以及对抗炎治疗无反应,促使对潜在疾病过程进行重新评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab1a/12213035/463084d9b575/CRIGM2025-6697889.001.jpg

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