Peng Wenting, Li Kaiwei, Song Yuhao, Zhu Ye
（ 610041） Department of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, China.
Sichuan Da Xue Xue Bao Yi Xue Ban. 2025 Mar 20;56(2):591-595. doi: 10.12182/20250360610.
The incidence of hypertriglyceridemic acute pancreatitis (HTG-AP) has been gradually rising in recent years. According to published findings, high triglyceride levels are strongly associated with the severity of acute pancreatitis, and may lead to a higher incidence of complications and worse prognosis. However, the risk factors associated with HTG-AP have not been systematically explored. Early identification and effective management of high triglyceride levels and other potential causes thereof are crucial for reducing the recurrence of acute pancreatitis in clinical practice. Herein, we reviewed the predictive factors of HTG-AP from the perspectives of etiology, pathogenesis, and the relevant biomarkers, such as C-reactive protein, Ca, PT, and D-dimer. We aim to provide important early warning signals for clinicians, thereby helping develop personalized treatment protocols and building a more accurate risk prediction model.
近年来，高甘油三酯血症性急性胰腺炎（HTG-AP）的发病率呈逐渐上升趋势。根据已发表的研究结果，高甘油三酯水平与急性胰腺炎的严重程度密切相关，可能导致更高的并发症发生率和更差的预后。然而，与HTG-AP相关的危险因素尚未得到系统研究。在临床实践中，早期识别并有效控制高甘油三酯水平及其潜在病因，对于降低急性胰腺炎的复发至关重要。在此，我们从病因、发病机制以及相关生物标志物（如C反应蛋白、钙、凝血酶原时间和D-二聚体）等角度，对HTG-AP的预测因素进行了综述。我们旨在为临床医生提供重要的早期预警信号，从而帮助制定个性化治疗方案，并构建更准确的风险预测模型。
