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扩张型冠状动脉介入治疗中的陷阱:一例报告

INTERVENTIONAL TRAPS IN ECTATIC CORONARY ARTERIES: A CASE REPORT.

作者信息

Gabaldo Krešimir, Knežević Praveček Marijana, Vučić Domagoj, Mišković Domagoj, Bitunjac Ivan, Dunđer Ivica, Vujeva Božo, Miškić Blaženka, Cvitkušić Lukenda Katica

机构信息

Department of Internal Medicine, Dr. Josip Benčević General Hospital, Slavonski Brod, Croatia.

Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.

出版信息

Acta Clin Croat. 2024 Mar;63(Suppl1):70-74. doi: 10.20471/acc.2024.63.s1.13.

Abstract

Coronary artery ectasia or aneurysms are dilatation of an arterial segment to a diameter at least 1.5 times that of the adjacent normal. Blood flow through such arteries is disturbed and turbulent, which, with the activation of endothelium, leads to chronic thrombosis in the blood vessel wall. Percutaneous coronary interventions in ectatic / aneurysmal vessels carry a high risk of complications, primarily a "no-reflow" phenomenon. No-reflow is common in patients with acute coronary syndrome, especially ST elevation myocardial infarction (STEMI). In this article, we present the occurrence of the no-reflow phenomenon in a stable patient undergoing percutaneous intervention due to a significant stenosis of the aneurysmally altered right coronary artery. Despite the rapid placement and optimization of stents and the applied drug therapy combined with thromboaspiration periprocedurally, it was not possible to establish TIMI 3 flow. However, after the initial failure and development of periprocedural STEMI, the patient was successfully stabilized with unexpectedly good recovery of infarcted myocardial function. Control coronarography 6 weeks after the initial event confirmed a proper stent patency with normal TIMI 3 flow.

摘要

冠状动脉扩张或动脉瘤是指动脉节段扩张至直径至少为相邻正常节段的1.5倍。流经此类动脉的血流受到干扰且呈湍流状态,这会激活内皮细胞,进而导致血管壁慢性血栓形成。对扩张/动脉瘤样血管进行经皮冠状动脉介入治疗会带来较高的并发症风险,主要是“无复流”现象。无复流在急性冠状动脉综合征患者中很常见,尤其是ST段抬高型心肌梗死(STEMI)患者。在本文中,我们介绍了一名稳定患者在因动脉瘤样改变的右冠状动脉严重狭窄而接受经皮介入治疗时出现无复流现象的情况。尽管在围手术期迅速置入并优化了支架,且应用了药物治疗并结合血栓抽吸,但仍无法实现TIMI 3级血流。然而,在最初失败并出现围手术期STEMI后,患者成功实现稳定,梗死心肌功能恢复情况出乎意料地良好。首次事件发生6周后的冠状动脉造影复查证实支架通畅良好,TIMI血流为正常3级。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17cb/12207849/eb15e177f53d/acc-63_supp1-70-f1.jpg

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