Shi Shuna, Wang Limei, Luo Haiyang, Fu Zhenling, Liu Yutao
Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, Henan, China.
Front Neurol. 2025 Jun 17;16:1573667. doi: 10.3389/fneur.2025.1573667. eCollection 2025.
To verify the hypothesis that length and inclination angle of the styloid process may lead to cerebral infarction related to carotid artery dissection through comparison of the length and inclination angle of the styloid process in middle-aged and young stroke patients undergoing carotid artery dissection, vertebral artery dissection, and non-dissection controls.
This was a Retrospective, single-center, case-control study that enrolled patients with cerebral infarction related to internal carotid artery dissection, vertebral artery dissection, and non-dissection controls. Eighteen patients with carotid artery dissection patients (cases) were compared with 34 sex-matched patients with vertebral artery dissection (G1) and 55 sex-matched patients without dissection (G2). The length and inclination angle of the styloid process were measured using Computed tomography angiography images. Differences between groups were estimated using the Student's test.
Styloid process length ipsilateral to the carotid artery dissection was not significantly longer than that of the contralateral side of the cases ( > 0.05), or to those of the ipsilateral and contralateral sides in patients with vertebral artery dissection ( > 0.05). The styloid process length ipsilateral to the dissection was significantly longer than those of the left and right sides of control patients ( < 0.05 for both), while the inclination angle of the cases was significantly larger than those of the ipsilateral and contralateral sides of the vertebral artery dissection patients ( < 0.05), and to the left and right sides of control patients (both < 0.05).
Long styloid process length and a large inclination angle appear to be risk factors for carotid artery dissection (CAD).
通过比较发生颈动脉夹层、椎动脉夹层的中青年卒中患者以及非夹层对照患者的茎突长度和倾斜角度，验证茎突长度和倾斜角度可能导致与颈动脉夹层相关的脑梗死这一假说。
这是一项回顾性、单中心病例对照研究，纳入了与颈内动脉夹层、椎动脉夹层相关的脑梗死患者以及非夹层对照患者。将18例颈动脉夹层患者（病例组）与34例性别匹配的椎动脉夹层患者（G1组）和55例性别匹配的无夹层患者（G2组）进行比较。使用计算机断层血管造影图像测量茎突的长度和倾斜角度。采用Student检验评估组间差异。
颈动脉夹层同侧的茎突长度与病例组对侧相比无显著延长（>0.05），与椎动脉夹层患者同侧和对侧相比也无显著延长（>0.05）。夹层同侧的茎突长度显著长于对照患者的左侧和右侧（两者均<0.05），而病例组的倾斜角度显著大于椎动脉夹层患者同侧和对侧的倾斜角度（<0.05），以及对照患者的左侧和右侧（均<0.05）。
茎突长度过长和倾斜角度过大似乎是颈动脉夹层（CAD）的危险因素。
