Abdelhalim Ahmed Reda, Ali Hossam Tharwat, Zakher Bishoy Adel Kamel, Ashour Yara
Faculty of Medicine Alexandria University Alexandria Egypt.
Qena Faculty of Medicine South Valley University Qena Egypt.
Clin Case Rep. 2025 Jul 1;13(7):e70580. doi: 10.1002/ccr3.70580. eCollection 2025 Jul.
Syringomyelia has several possible causes, commonly including Chiari malformation, spinal cord tumors and injuries, and damage caused by lesions around the spinal cord. A 34-year-old female was diagnosed with primary breast cancer and vertebral metastasis and was initiated on an extensive regimen of chemotherapy and radiotherapy. A few months later, she developed numbness and weakness in her lower limbs, and she was concluded to have syringomyelia with surrounding atrophic myelopathy along with vertebral metastasis. Patients developing neurological symptoms following radiotherapy or chemotherapy should be thoroughly evaluated, and further cases should be reported in the literature.
脊髓空洞症有多种可能的病因，常见的包括Chiari畸形、脊髓肿瘤和损伤，以及脊髓周围病变引起的损害。一名34岁女性被诊断为原发性乳腺癌并伴有椎体转移，开始接受广泛的化疗和放疗方案。几个月后，她出现下肢麻木和无力，最终被诊断为脊髓空洞症伴周围萎缩性脊髓病以及椎体转移。放疗或化疗后出现神经症状的患者应进行全面评估，更多病例应在文献中报道。
