Hao-Yu Dai, Yi-Wei Cao, Shao-Ke Li, Dong-Liang Lin, Cun-Zhi Lin, Bao-Hong Xiao
Oncology (Williston Park). 2025 Jun 16;null(5):198-203. doi: 10.46883/2025.25921043.
Extranodal natural killer (NK)/T-cell lymphoma (ENKTL) is highly invasive. Its etiology and pathogenesis may be related to Epstein-Barr virus infection. In this article, we report a case of a man with ENKTL affecting the right vocal cord and right lung. Initially, the lesion was misdiagnosed as a pulmonary infection. However, subsequent histopathological examinations confirmed the diagnosis through analysis of a surgically resected specimen. Following 14 cycles of immune therapy and chemotherapy, the lesion in the right lung significantly shrank. This case underscored the importance of obtaining surgically resected specimens for pathology when ENKTL is suspected, which can improve diagnostic accuracy and mitigate misdiagnosis.
结外自然杀伤(NK)/T细胞淋巴瘤(ENKTL)具有高度侵袭性。其病因和发病机制可能与爱泼斯坦-巴尔病毒感染有关。在本文中,我们报告了一例男性ENKTL患者,病变累及右侧声带和右肺。起初,该病变被误诊为肺部感染。然而,随后的组织病理学检查通过对手术切除标本的分析确诊了病情。经过14个周期的免疫治疗和化疗后,右肺病变明显缩小。该病例强调了在怀疑为ENKTL时获取手术切除标本进行病理检查的重要性,这有助于提高诊断准确性并减少误诊。