This study investigates the mechanistic basis of follicular co-dominance in goats by evaluating the differential expression of gonadotropin receptors and associated functional markers across follicle sizes. Granulosa (GC) and theca cells (TC) were isolated from small (<5.0 mm), medium (5.1-7.0 mm), and large (>7.0 mm) follicles obtained from abattoir-sourced ovaries of sub-tropical Beetal goats. Transcripts of luteinizing hormone receptor (LHR), follicle-stimulating hormone receptor (FSHR), steroidogenic enzymes (CYP19A1, CYP17A1), growth (IGF-1), apoptotic (BAX), and anti-apoptotic (Bcl-2) markers were quantified using RT-qPCR. Receptor density and percentage of LHR- and FSHR-positive GC were analyzed via flow cytometry. Intrafollicular estradiol-17β and progesterone concentrations were measured by radioimmunoassay. LHR expression was significantly elevated in GC of medium follicles and in TC of small and medium follicles. FSHR transcripts were significantly abundant in GC of small follicles. Flow cytometry revealed that medium follicles exhibited the highest percentage and mean fluorescence intensity (MFI) for both FSHR and LHR, suggesting dual gonadotropin sensitivity. Estradiol-17β and progesterone concentrations were also significantly higher in medium compared to small follicles, consistent with enhanced steroidogenic activity. CYP19A1 expression peaked in GC of small follicles, while CYP17A1 was elevated in TC of small and medium follicles. Bcl-2 expression was higher in medium follicles than in large follicles, while IGF-1 and BAX expression remained unchanged across sizes. These findings provide novel insight into goat follicular physiology, supporting the hypothesis that medium follicles co-express both gonadotropin receptors, potentially enabling co-dominance through dual hormonal responsiveness.