Subedi Ram Prasad, Yogi Nikunja, Thulung Suraj, Bishokarma Suresh, Thakali Ajit, Yogi Sadikshya
Department of Neurosurgery, Upendra Devkota Memorial National Institute of Neurological and Allied Sciences (UDM-NINAS), Bansbari, Kathmandu, Nepal.
Department of Neurosurgery, Upendra Devkota Memorial National Institute of Neurological and Allied Sciences (UDM-NINAS), Bansbari, Kathmandu, Nepal.
Int J Surg Case Rep. 2025 Aug;133:111591. doi: 10.1016/j.ijscr.2025.111591. Epub 2025 Jun 30.
Mycotic aneurysms are a rare but serious complication of systemic infections such as infective endocarditis. When ruptured, they carry a high risk of mortality and are an uncommon cause of intracerebral hemorrhage.
A 54-year-old male, initially presented with a right Middle Cerebral Artery (MCA) territory infarct and was managed conservatively. He later developed an intracerebral hemorrhage requiring surgical evacuation, followed by a second hemorrhagic event. Digital Angiography revealed a ruptured mycotic pseudoaneurysm in the right MCA M4 segment; he was managed conservatively with antibiotics and recovered well by three- month follow up.
Mycotic aneurysms are though rare but can be managed medically with early detection and prompt diagnosis. Multidisciplinary team of Neurologists, neurointerventionist, cardiologists, radiologists, clinical psychologist discussion is needed for timely diagnosis of such illness and appropriate treatment. Patient with hemodynamically stable status, small hematoma, can be managed conservatively with antibiotics whereas massive hematoma, ruptured aneurysm needs surgical or endovascular treatments.
Prompt and thorough radiological assessment-including non-contrast CT of the brain and cerebral angiography, coupled with detailed cardiac evaluation such as echocardiography, is pivotal in the early detection of mycotic aneurysm in patients presenting with intracerebral hemorrhage. Such a comprehensive diagnostic approach not only facilitates timely intervention but also significantly contributes to improved clinical outcomes. Treatment should be tailored according to the clinical condition of each patient.
霉菌性动脉瘤是感染性心内膜炎等全身感染的一种罕见但严重的并发症。破裂时,它们具有很高的死亡风险,是脑出血的罕见原因。
一名54岁男性,最初表现为右侧大脑中动脉(MCA)供血区梗死,接受了保守治疗。他后来发生脑出血,需要手术清除血肿,随后又发生了第二次出血事件。数字血管造影显示右侧大脑中动脉M4段有一个破裂的霉菌性假性动脉瘤;他接受了抗生素保守治疗,三个月随访时恢复良好。
霉菌性动脉瘤虽然罕见,但通过早期发现和及时诊断可以进行药物治疗。需要神经科医生、神经介入专家、心脏病专家、放射科医生、临床心理学家组成的多学科团队进行讨论,以便及时诊断此类疾病并进行适当治疗。血流动力学稳定、血肿较小的患者可以用抗生素保守治疗,而巨大血肿、动脉瘤破裂的患者则需要手术或血管内治疗。
及时、全面的影像学评估——包括脑部非增强CT和脑血管造影,以及详细的心脏评估,如超声心动图,对于脑出血患者霉菌性动脉瘤的早期检测至关重要。这种全面的诊断方法不仅有助于及时干预,还能显著改善临床结果。治疗应根据每个患者的临床情况进行调整。