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Viewing MASLD through an integrative gut microbiome lens.

作者信息

Wen Weijie, Yang Changqing, Zuo Tao

机构信息

Guangdong Institute of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Key Laboratory of Human Microbiome and Chronic Diseases (Sun Yat-sen University), Ministry of Education, Guangzhou, China.

出版信息

Nat Metab. 2025 Jul 2. doi: 10.1038/s42255-025-01300-2.

DOI:10.1038/s42255-025-01300-2
PMID:40604155
Abstract
摘要

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本文引用的文献

1
The oral-gut microbiome axis in health and disease.口腔-肠道微生物轴在健康和疾病中的作用。
Nat Rev Microbiol. 2024 Dec;22(12):791-805. doi: 10.1038/s41579-024-01075-5. Epub 2024 Jul 22.
2
The gut ileal mucosal virome is disturbed in patients with Crohn's disease and exacerbates intestinal inflammation in mice.肠回肠黏膜病毒组在克罗恩病患者中受到干扰，并在小鼠中加剧肠道炎症。
Nat Commun. 2024 Feb 22;15(1):1638. doi: 10.1038/s41467-024-45794-y.
3
Gut bacteriophages ignite mammalian immunity.肠道噬菌体激发哺乳动物免疫力。
Nat Rev Microbiol. 2023 Oct;21(10):634. doi: 10.1038/s41579-023-00911-4.
4
Roles of the gut virome and mycobiome in faecal microbiota transplantation.肠道病毒组和真菌组在粪便微生物群移植中的作用。
Lancet Gastroenterol Hepatol. 2022 May;7(5):472-484. doi: 10.1016/S2468-1253(21)00303-4. Epub 2022 Mar 8.
5
Dynamic Alterations of the Gut Microbial Pyrimidine and Purine Metabolism in the Development of Liver Cirrhosis.肝硬化发展过程中肠道微生物嘧啶和嘌呤代谢的动态变化
Front Mol Biosci. 2022 Jan 28;8:811399. doi: 10.3389/fmolb.2021.811399. eCollection 2021.
6
Mechanisms and disease consequences of nonalcoholic fatty liver disease.非酒精性脂肪性肝病的机制及疾病后果
Cell. 2021 May 13;184(10):2537-2564. doi: 10.1016/j.cell.2021.04.015.
7
Assessing the role of amino acids in systemic inflammation and organ failure in patients with ACLF.评估氨基酸在慢加急性肝衰竭患者全身炎症和器官衰竭中的作用。
J Hepatol. 2021 May;74(5):1117-1131. doi: 10.1016/j.jhep.2020.11.035. Epub 2020 Dec 1.
8
Altered serum acylcarnitine profile is associated with the status of nonalcoholic fatty liver disease (NAFLD) and NAFLD-related hepatocellular carcinoma.血清酰基肉碱谱的改变与非酒精性脂肪性肝病（NAFLD）和 NAFLD 相关的肝细胞癌的状态有关。
Sci Rep. 2019 Jul 23;9(1):10663. doi: 10.1038/s41598-019-47216-2.
9
Gut mucosal virome alterations in ulcerative colitis.溃疡性结肠炎患者的肠道黏膜病毒组改变。
Gut. 2019 Jul;68(7):1169-1179. doi: 10.1136/gutjnl-2018-318131. Epub 2019 Mar 6.
10
Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis.噬菌体的扩张与肠道炎症和结肠炎的加重有关。
Cell Host Microbe. 2019 Feb 13;25(2):285-299.e8. doi: 10.1016/j.chom.2019.01.008.