Wang Yaohui, Zhou Guyue, Chen Haoran, Wu Pengfei, Yang Wenhui, Liu Feng, Wang Qiuliang
Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, 100190, China.
School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing, 100049, China.
Npj Imaging. 2024 Dec 11;2(1):54. doi: 10.1038/s44303-024-00060-0.
Animal magnetic resonance imaging (MRI) systems typically deliver superior imaging performance over conventional human MRI systems, making them a prevailing instrument in preclinical research. It is challenging to achieve the high performance of these animal MRI systems, due to the multifaceted nature of the various system components and the complexity of integration debugging. This work described the design, fabrication, measurement and integration of a 7 T animal MRI system, which exhibits several performance highlights. Both the magnet and gradient assembly adopted an ultra-shielding strategy, facilitating ease of system installation, maintenance and debugging. The main magnetic field exhibits acceptable homogeneity and stability, and the gradient coil is mechanically reliable thanks to zero-force control. The animal MRI system underwent debugging using proprietary imaging software to generate images of phantoms, fruits and organisms. Further research investigation will be performed to promote more scientific outputs with enhanced functional capabilities.
动物磁共振成像（MRI）系统通常比传统的人类MRI系统具有更卓越的成像性能，这使其成为临床前研究中的主流仪器。由于各种系统组件具有多方面的特性以及集成调试的复杂性，要实现这些动物MRI系统的高性能具有挑战性。这项工作描述了一台7T动物MRI系统的设计、制造、测量和集成，该系统具有几个性能亮点。磁体和梯度组件均采用了超屏蔽策略，便于系统的安装、维护和调试。主磁场具有可接受的均匀性和稳定性，并且由于采用了零力控制，梯度线圈在机械上是可靠的。该动物MRI系统使用专有成像软件进行调试，以生成体模、水果和生物体的图像。将进行进一步的研究调查，以通过增强功能来促进产生更多的科学成果。
