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Mapping the human prostate at the cellular level.

作者信息

Cussenot Olivier

机构信息

Universitätsklinik für Urologie Medical University Vienna, Vienna, Austria.

出版信息

Nat Rev Urol. 2025 Jul 2. doi: 10.1038/s41585-025-01057-z.

DOI:10.1038/s41585-025-01057-z

PMID:40604311

Abstract

摘要

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本文引用的文献

Spatially resolved transcriptomic analysis of the adult human prostate.

Nat Genet. 2025 Apr;57(4):922-933. doi: 10.1038/s41588-025-02139-9. Epub 2025 Apr 1.

Spatial transcriptomics identifies candidate stromal drivers of benign prostatic hyperplasia.

JCI Insight. 2024 Jan 23;9(2):e176479. doi: 10.1172/jci.insight.176479.

Prostate zones and cancer: lost in transition?

Nat Rev Urol. 2022 Feb;19(2):101-115. doi: 10.1038/s41585-021-00524-7. Epub 2021 Oct 19.

A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors.

Elife. 2020 Sep 11;9:e59465. doi: 10.7554/eLife.59465.

A Cellular Anatomy of the Normal Adult Human Prostate and Prostatic Urethra.

Cell Rep. 2018 Dec 18;25(12):3530-3542.e5. doi: 10.1016/j.celrep.2018.11.086.

Comprehensive molecular classification of localized prostate adenocarcinoma reveals a tumour subtype predictive of non-aggressive disease.

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Spatial maps of prostate cancer transcriptomes reveal an unexplored landscape of heterogeneity.

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Stem/progenitor and intermediate cell types and the origin of human prostate cancer.

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